2012
HIV-1-Related Central Nervous System Disease: Current Issues in Pathogenesis, Diagnosis, and Treatment
Spudich S, González-Scarano F. HIV-1-Related Central Nervous System Disease: Current Issues in Pathogenesis, Diagnosis, and Treatment. Cold Spring Harbor Perspectives In Medicine 2012, 2: a007120. PMID: 22675662, PMCID: PMC3367536, DOI: 10.1101/cshperspect.a007120.Peer-Reviewed Original ResearchConceptsHIV infectionLate-stage HIV infectionCentral nervous system injuryOptimal antiretroviral therapyNeuropathogenesis of HIVTreatment of HIVNervous system injuryLong-term survivalAntiretroviral therapyCNS complicationsAntiretroviral medicationsViral neuroinvasionSystem injuryCNS injuryClinical studiesNeurological abnormalitiesUnderresourced settingsNeuropsychological testingHIVInfectionSubstantial proportionTherapyInjuryTreatmentCurrent era
2011
Central nervous system complications of HIV infection.
Spudich SS, Ances BM. Central nervous system complications of HIV infection. Topics In Antiviral Medicine 2011, 19: 48-57. PMID: 21868822, PMCID: PMC6148949.Peer-Reviewed Original ResearchConceptsNervous systemCentral nervous system complicationsNervous system complicationsEarly treatment interventionStudy of pathogenesisCentral nervous systemBiomarkers of HANDDisease activityAdjunctive therapyNeurologic injuryHIV infectionOpportunistic infectionsSystem complicationsNeurologic disordersNeurocognitive disordersEtiology of diseaseMeasurable biomarkersEarly infectionTreatment interventionsInfectionHIVBiomarkersDisordersTreatmentNovel molecules