1999
A chemogenetic approach to RNA function/structure analysis
Strobel S. A chemogenetic approach to RNA function/structure analysis. Current Opinion In Structural Biology 1999, 9: 346-352. PMID: 10361087, DOI: 10.1016/s0959-440x(99)80046-3.Peer-Reviewed Original ResearchNucleotide Analog Interference Mapping
Ryder S, Strobel S. Nucleotide Analog Interference Mapping. Methods 1999, 18: 38-50. PMID: 10208815, DOI: 10.1006/meth.1999.0755.Peer-Reviewed Original ResearchConceptsFunctional groupsActive moleculesGroup substitutionNucleotide analog interference mappingIncorporation propertiesIndividual analoguesMoleculesSeries 5AnaloguesSubstitution experimentsGel electrophoresisInterference mappingUnique biochemical signatureSubstitutionSynthesisNucleoside analog triphosphatesActivity assaysBiochemical informationReactionAnalog substitutionsAssayable functionChemogenetic approachRNA structureNucleotide analoguesIodine
1998
Identifying RNA Minor Groove Tertiary Contacts by Nucleotide Analogue Interference Mapping with N 2-Methylguanosine †
Ortoleva-Donnelly L, Kronman M, Strobel S. Identifying RNA Minor Groove Tertiary Contacts by Nucleotide Analogue Interference Mapping with N 2-Methylguanosine †. Biochemistry 1998, 37: 12933-12942. PMID: 9737873, DOI: 10.1021/bi980723j.Peer-Reviewed Original ResearchThe chemical basis of adenosine conservation throughout the Tetrahymena ribozyme.
Ortoleva-Donnelly L, Szewczak A, Gutell R, Strobel S. The chemical basis of adenosine conservation throughout the Tetrahymena ribozyme. RNA 1998, 4: 498-519. PMID: 9582093, PMCID: PMC1369635, DOI: 10.1017/s1355838298980086.Peer-Reviewed Original Research
1997
Defining the chemical groups essential for Tetrahymena group I intron function by nucleotide analog interference mapping
Strobel S, Shetty K. Defining the chemical groups essential for Tetrahymena group I intron function by nucleotide analog interference mapping. Proceedings Of The National Academy Of Sciences Of The United States Of America 1997, 94: 2903-2908. PMID: 9096319, PMCID: PMC20295, DOI: 10.1073/pnas.94.7.2903.Peer-Reviewed Original Research