2014
The Effect of Surgeon Experience on the Detection of Metastatic Lymph Nodes in the Central Compartment and the Pathologic Features of Clinically Unapparent Metastatic Lymph Nodes: What Are We Missing When We Don't Perform a Prophylactic Dissection of Central Compartment Lymph Nodes in Papillary Thyroid Cancer?
Scherl S, Mehra S, Clain J, Dos Reis LL, Persky M, Turk A, Wenig B, Husaini H, Urken ML. The Effect of Surgeon Experience on the Detection of Metastatic Lymph Nodes in the Central Compartment and the Pathologic Features of Clinically Unapparent Metastatic Lymph Nodes: What Are We Missing When We Don't Perform a Prophylactic Dissection of Central Compartment Lymph Nodes in Papillary Thyroid Cancer? Thyroid 2014, 24: 1282-1288. PMID: 24787362, DOI: 10.1089/thy.2013.0600.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedAged, 80 and overCarcinomaCarcinoma, PapillaryFalse Negative ReactionsFalse Positive ReactionsFemaleHashimoto DiseaseHumansIntraoperative PeriodLymph NodesLymphatic MetastasisMaleMiddle AgedNeck DissectionProfessional CompetenceRiskSensitivity and SpecificitySurgeonsThyroid Cancer, PapillaryThyroid NeoplasmsThyroidectomyYoung AdultConceptsProphylactic central neck dissectionPapillary thyroid cancerMetastatic lymph nodesExtranodal extensionLymph nodesOccult metastasesPositive nodesSurgeon experienceOccult nodesPathologic featuresThyroid cancerPresence of ENECentral compartment lymph nodesAdverse histologic featuresMultiple positive nodesPositive central nodesSenior surgeon's assessmentCentral neck dissectionFalse-negative casesGroup of surgeonsEvident nodesPreoperative evidenceProphylactic dissectionNeck dissectionRisk stratificationExtrathyroidal Extension Predicts Extranodal Extension in Patients with Positive Lymph Nodes: An Important Association That May Affect Clinical Management
Clain JB, Scherl S, Dos Reis L, Turk A, Wenig BM, Mehra S, Karle WE, Urken ML. Extrathyroidal Extension Predicts Extranodal Extension in Patients with Positive Lymph Nodes: An Important Association That May Affect Clinical Management. Thyroid 2014, 24: 951-957. PMID: 24443878, DOI: 10.1089/thy.2013.0557.Peer-Reviewed Original ResearchConceptsExtranodal extensionLymph nodesPrimary tumorPresence of ENEAmerican Pathologists (CAP) protocolNode-positive patientsPositive lymph nodesRecurrent lymph nodesUpstaging of patientsMajority of patientsAggressive disease biologyLong-term survivalPresence of extensionCompletion thyroidectomyPositive nodesNodal metastasisRetrospective reviewHistologic featuresClinical managementDisease aggressivenessThyroid cancerT4 casesThyroid carcinomaHigh incidencePatients
2012
Cervical metastasis of germ cell tumors: Evaluation, management, complications, and outcomes
Mehra S, Liu J, Gupta A, Sheinfeld J, Kraus D. Cervical metastasis of germ cell tumors: Evaluation, management, complications, and outcomes. The Laryngoscope 2012, 122: 286-290. PMID: 22252920, DOI: 10.1002/lary.22422.Peer-Reviewed Original ResearchConceptsDisease-specific survivalRetrospective chart reviewNeck massChart reviewConsecutive patientsInitial diagnosisSingle-institution retrospective chart reviewDiagnosis of GCTResidual neck massesPercent of patientsSecondary end pointsPreoperative tumor markersPermanent nerve injuryGerm cell tumorsCervical controlMetastatic GCTNeck recurrenceCervical metastasisPositive nodesPresenting symptomChyle leakNerve injuryTumor metastaticLimited complicationsOperative management