2024
Complex Congenital Heart Disease in the Adult
Goldstein S, Krasuski R. Complex Congenital Heart Disease in the Adult. Annual Review Of Medicine 2024, 75: 493-512. PMID: 38285514, DOI: 10.1146/annurev-med-050922-052324.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsCongenital heart diseaseAdult congenital heart diseaseComplex congenital heart diseaseHeart diseaseSevere birth defectsStructural abnormalitiesBirth defectsComplex lesionsFrequent causeHigh riskImprove outcomesPediatric outcomesHeterogeneous groupPalliative interventionsCardiovascular systemDiseaseAdultsOutcomesComplications
2022
Pulmonary Hypertension in Adults with Congenital Heart Disease
Goldstein S, Krasuski R. Pulmonary Hypertension in Adults with Congenital Heart Disease. Cardiology Clinics 2022, 40: 55-67. PMID: 34809917, DOI: 10.1016/j.ccl.2021.08.006.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsPAH-CHDPulmonary arterial hypertension related to congenital heart diseaseSystemic-to-pulmonary shuntAssociated with significant morbidityCongenital heart diseasePulmonary vascular resistancePulmonary vascular remodelingShunt reversalEisenmenger syndromePulmonary hypertensionCentral cyanosisPrimary management strategySignificant morbidityMedical therapySevere elevationVascular resistanceDefect closureSevere phenotypeVascular remodelingHeart diseasePathological processesShuntCyanosisAdultsHypoxemia
2020
Causes of Death and Cardiovascular Comorbidities in Adults With Congenital Heart Disease
Goldstein S, D’Ottavio A, Spears T, Chiswell K, Hartman R, Krasuski R, Kemper A, Meyer R, Hoffman T, Walsh M, Sang C, Paolillo J, Li J. Causes of Death and Cardiovascular Comorbidities in Adults With Congenital Heart Disease. Journal Of The American Heart Association 2020, 9: e016400. PMID: 32654582, PMCID: PMC7660712, DOI: 10.1161/jaha.119.016400.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overCause of DeathCohort StudiesComorbidityFemaleHeart Defects, CongenitalHumansMaleNorth CarolinaRisk FactorsConceptsCongenital heart diseaseSevere congenital heart diseaseMedian ageNonsevere CHDPresence of cardiovascular comorbiditiesHeart diseaseCardiovascular risk factorsNon-CHD causesIschemic heart diseaseElectronic medical record dataDeath certificate dataCause of deathNonsevere diseaseContemporary cohortValvular lesionsCardiovascular comorbidityCardiovascular comorbiditiesResults PatientsCardiovascular deathMedical record dataRisk factorsSevere groupLesion severityPatientsCertificate data
2017
Congenital and Acquired Valvular Heart Disease in Pregnancy
Goldstein S, Ward C. Congenital and Acquired Valvular Heart Disease in Pregnancy. Current Cardiology Reports 2017, 19: 96. PMID: 28840470, DOI: 10.1007/s11886-017-0910-6.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsMeSH KeywordsFemaleHeart Defects, CongenitalHeart Valve DiseasesHemodynamicsHumansPregnancyPregnancy Complications, CardiovascularRheumatic Heart DiseaseConceptsValvular heart diseaseHeart diseaseRisk of pregnancy-related complicationsManagement of valvular heart diseaseWomen of childbearing agePregnancy-related complicationsAcquired valvular heart diseaseRheumatic heart diseaseValvular abnormalitiesCongenital abnormalitiesCase reportSymptomatic diseaseChildbearing ageRegurgitant lesionsHemodynamic effectsPatient populationPregnancyPercutaneous interventionStenotic lesionsRefractory symptomsHigh riskObservational studyReviewThe numberDiseaseAbnormalities