2024
Prolonged length of stay and omission of adjuvant therapy are associated with early mortality after pancreatic adenocarcinoma resection
Ying L, Ilagan-Ying Y, Kunstman J, Peters N, Almeida M, Blackburn H, Ferrucci L, Billingsley K, Khan S, Chhoda A, John N, Salem R, Sharma A, Ahuja N. Prolonged length of stay and omission of adjuvant therapy are associated with early mortality after pancreatic adenocarcinoma resection. Surgical Oncology Insight 2024, 1: 100007. DOI: 10.1016/j.soi.2024.100007.Peer-Reviewed Original ResearchFactors associated with early mortalityCases of pancreatic adenocarcinomaPancreatic adenocarcinoma resectionRisk of early mortalityLength of stayEarly mortalityAdjuvant chemotherapyPancreatic adenocarcinomaChemotherapy utilizationAdenocarcinoma resectionRisk factors associated with early mortalityOmission of adjuvant therapyNon-metastatic pancreatic adenocarcinomaMultivariate Cox regression modelAssociated with early mortalityPost-resection survivalIncreased risk of early mortalityParticipant Use FileProlonged hospital stayProlonged length of stayAdjuvant chemotherapy utilizationDecrease perioperative complicationsCox regression modelsNon-academic centersHospital risk factors
2018
Review and current state of radiation therapy for locally advanced pancreatic adenocarcinoma
Blakaj A, Stein SM, Khan SA, Johung KL. Review and current state of radiation therapy for locally advanced pancreatic adenocarcinoma. Journal Of Gastrointestinal Oncology 2018, 9: 1027-1036. PMID: 30603121, PMCID: PMC6286948, DOI: 10.21037/jgo.2018.03.07.Peer-Reviewed Original ResearchStereotactic body radiation therapyManagement of LAPCRadiation therapyPancreatic cancerGood treatment tolerabilityProgressive local diseaseAdvanced pancreatic adenocarcinomaAdvanced pancreatic cancerEffective systemic therapyOverall poor prognosisBody radiation therapyTime of deathAreas of controversyTreatment tolerabilityLocal progressionSystemic regimensSurvival benefitSystemic therapyDose escalationImmune therapySignificant morbidityLocal diseasePoor prognosisOptimal treatmentPancreatic adenocarcinoma