2024
EPCO-35. GENOMIC CHARACTERIZATION OF GROWTH HORMONE SECRETING PITUITARY ADENOMAS
Alanya H, Yalcin K, Hilton B, Gultekin B, Mishra-Gorur K, McGuone D, Gunel M, Omay S, Erson-Omay Z. EPCO-35. GENOMIC CHARACTERIZATION OF GROWTH HORMONE SECRETING PITUITARY ADENOMAS. Neuro-Oncology 2024, 26: viii9-viii9. PMCID: PMC11553213, DOI: 10.1093/neuonc/noae165.0034.Peer-Reviewed Original ResearchGH-secreting pituitary adenomasWhole-exome sequencingPituitary adenomasGNAS mutationsCopy number variationsSporadic GH-secreting pituitary adenomasGrowth hormone (GH)-secreting pituitary adenomasGenomic profilingGrowth hormone secreting pituitary adenomaSecreting pituitary adenomasBlood samplesComprehensive genomic characterizationSomatic GNAS mutationsSingle nucleotide variantsMatched blood samplesGenomic instabilityAssessment of genomic instabilityStatistically significant differenceTumor sizeClinical featuresTumor samplesClinical dataTumorExome sequencingBrain tumors
2023
Primary hypothyroidism presenting as neuropsychiatric symptoms and pituitary enlargement in a young woman: illustrative case
Haider S, Templeton K, Omay S, Inzucchi S. Primary hypothyroidism presenting as neuropsychiatric symptoms and pituitary enlargement in a young woman: illustrative case. Journal Of Neurosurgery Case Lessons 2023, 5: case22496. PMID: 36794728, PMCID: PMC10550602, DOI: 10.3171/case22496.Peer-Reviewed Original ResearchPituitary enlargementPrimary hypothyroidismPituitary hyperplasiaElevated thyroid-stimulating hormoneSevere primary hypothyroidismThyroid-stimulating hormoneComputed tomography scanMagnetic resonance imagingLevothyroxine replacementHormone replacementNeuropsychiatric symptomsRare presentationSellar massSurgical interventionTomography scanCommon causePituitary adenomasPhysiological causesResonance imagingPsychiatry departmentYoung womenHypothyroidismHyperplasiaSymptomsEnlargement
2022
Staged endovascular treatment of a coexisting parasellar aneurysm and endoscopic resection of a pituitary macroadenoma: illustrative case
Nene A, Hong CS, McGuone D, Matouk CC, Omay SB. Staged endovascular treatment of a coexisting parasellar aneurysm and endoscopic resection of a pituitary macroadenoma: illustrative case. Journal Of Neurosurgery Case Lessons 2022, 3: case21699. PMID: 36130536, PMCID: PMC9379633, DOI: 10.3171/case21699.Peer-Reviewed Original Research
2020
Case Report: Suprasellar Pituitary Adenoma Presenting With Temporal Lobe Seizures
Hong CS, Gorrepati R, Kundishora AJ, Elsamadicy AA, Peter PR, Damisah EC, Manes RP, Omay SB. Case Report: Suprasellar Pituitary Adenoma Presenting With Temporal Lobe Seizures. Frontiers In Surgery 2020, 7: 598138. PMID: 33335912, PMCID: PMC7736041, DOI: 10.3389/fsurg.2020.598138.Peer-Reviewed Case Reports and Technical NotesPituitary macroadenomaTemporal lobeFurther seizure activityTemporal lobe seizuresYear old maleMass effectLeft temporal lobeSuprasellar pituitary adenomasEndocrine dysfunctionGeneralized seizuresSeizure activityPituitary pathologyPituitary adenomasMedical treatmentSeizuresEndoscopic endonasalMacroadenomasLobePatientsDysfunctionAdenomasSymptomsTumorsEndonasalPathology
2019
5 Suprasellar Pathology
Omay S, Anand V, Schwartz T. 5 Suprasellar Pathology. 2019, 61-69. DOI: 10.1007/978-3-319-64379-3_5.Peer-Reviewed Original ResearchSuprasellar lesionsCareful patient selectionVisual field lossEndonasal endoscopic approachEndocrine dysfunctionOptic nerveOptic apparatusPatient selectionSurgical interventionMicroneurosurgical approachesBrain retractionEndoscopic approachPituitary adenomasCarotid arteryEndoscopic methodsThird ventricleEndoscopic techniquesField lossPituitary glandSuprasellar pathologiesLesionsPathologyHydrocephalusTransplanumNerve
2017
Endonasal endoscopic pituitary surgery in the elderly.
Wilson PJ, Omay SB, Kacker A, Anand VK, Schwartz TH. Endonasal endoscopic pituitary surgery in the elderly. Journal Of Neurosurgery 2017, 128: 429-436. PMID: 28387628, DOI: 10.3171/2016.11.jns162286.Peer-Reviewed Original ResearchMeSH KeywordsAdenomaAgedAged, 80 and overBlood Loss, SurgicalDatabases, FactualFemaleHumansLength of StayMaleMiddle AgedNasal CavityNatural Orifice Endoscopic SurgeryNeurosurgical ProceduresPituitary GlandPituitary NeoplasmsPostoperative ComplicationsRetrospective StudiesSphenoid BoneTreatment OutcomeConceptsComplication rateEndonasal endoscopic surgeryElderly patientsPituitary adenomasEndoscopic surgeryEndoscopic endonasal transsphenoidal resectionAge groupsEndonasal transsphenoidal resectionSymptomatic subdural hygromasIntraoperative blood lossRisk of complicationsRisk of surgeryExtent of resectionSingle-center dataAverage tumor diameterHealthy young personsLength of stayEndonasal endoscopic pituitary surgeryEndonasal endoscopic approachEndoscopic pituitary surgeryCranial complicationsPostoperative hematomaSymptomatic patientsBlood lossRetrospective reviewReoperation for Growth-Hormone Secreting Pituitary Adenomas: Endonasal Endoscopic Series and Systematic Review of the Literature
Almeida J, Ruiz-Treviño A, Liang B, Shetty S, Chen Y, Omay S, Anand V, Schwartz T. Reoperation for Growth-Hormone Secreting Pituitary Adenomas: Endonasal Endoscopic Series and Systematic Review of the Literature. Journal Of Neurological Surgery Part B Skull Base 2017, 78: s1-s156. DOI: 10.1055/s-0037-1600584.Peer-Reviewed Original Research