2011
Detecting copy number status and uncovering subclonal markers in heterogeneous tumor biopsies
Parisi F, Ariyan S, Narayan D, Bacchiocchi A, Hoyt K, Cheng E, Xu F, Li P, Halaban R, Kluger Y. Detecting copy number status and uncovering subclonal markers in heterogeneous tumor biopsies. BMC Genomics 2011, 12: 230. PMID: 21569352, PMCID: PMC3114747, DOI: 10.1186/1471-2164-12-230.Peer-Reviewed Original ResearchConceptsCopy number statusMelanoma samplesSingle nucleotide polymorphism arrayHigh-throughput technologiesNext-generation sequencing dataHigh-throughput techniquesCopy number profilesHigh-throughput assaysNucleotide polymorphism arrayNumber statusCopy number alterationsTranscriptome sequencingNext-generation sequencingRNA-seqSingle exonSNP arraySequencing dataMelanoma cell linesNumerous aberrationsPolymorphism arrayNovel aberrationsNumber alterationsSubclonal heterogeneitySitu hybridizationAllelic imbalance
1991
Localization of Basic Fibroblast Growth Factor mRNA in Melanocytic Lesions by In Situ Hybridization
Scott G, Stoler M, Sarkar S, Halaban R. Localization of Basic Fibroblast Growth Factor mRNA in Melanocytic Lesions by In Situ Hybridization. Journal Of Investigative Dermatology 1991, 96: 318-322. PMID: 2002252, DOI: 10.1111/1523-1747.ep12465203.Peer-Reviewed Original ResearchConceptsBFGF gene transcriptsBasic fibroblast growth factorGene transcriptsCell populationsGrowth factorNormal human melanocytesDermal cell typesFibroblast growth factorHuman melanocytesCell typesParacrine growth factorCellular proliferationAberrant expressionSitu hybridizationMelanocytic lesionsMetastatic melanomaBasic FGF expressionFGF expressionGrowth independenceTranscriptsBasic fibroblast growth factor mRNADysplastic neviExpressionParacrine mechanismsMelanocytes