2020
VISUAL OUTCOME OF EARLY VITRECTOMY AND INTRAVITREAL ANTIBIOTICS IN ACUTE POSTSURGICAL AND POSTINTRAVITREAL INJECTION ENDOPHTHALMITIS: European Vitreo-Retinal Society Endophthalmitis Study Report Two.
Soliman MK, Gini G, Kuhn F, Parolini B, Ozdek S, Adelman RA, Sallam AB. VISUAL OUTCOME OF EARLY VITRECTOMY AND INTRAVITREAL ANTIBIOTICS IN ACUTE POSTSURGICAL AND POSTINTRAVITREAL INJECTION ENDOPHTHALMITIS: European Vitreo-Retinal Society Endophthalmitis Study Report Two. Retina 2020, 41: 423-430. PMID: 32467482, DOI: 10.1097/iae.0000000000002856.Peer-Reviewed Original ResearchConceptsIntravitreal antibioticsPPV groupEarly PPVVisual outcomeRetinal detachmentPostintravitreal injection endophthalmitisRetrospective multicenter cohortFinal visual acuityWeeks of presentationDays of presentationMethod of treatmentEarly vitrectomyMulticenter cohortIntravitreal injectionPlana vitrectomyRetina specialistsVisual acuityMean ageIntraocular proceduresEndophthalmitisSimilar outcomesLight perceptionEyesVitrectomyOutcomes
2019
International Practice Patterns for the Management of Acute Postsurgical and Postintravitreal Injection Endophthalmitis European Vitreo-Retinal Society Endophthalmitis Study Report 1
Soliman MK, Gini G, Kuhn F, Iros M, Parolini B, Ozdek S, Michalewska Z, Bopp S, Adelman RA, Sallam AB, Group E, Kardaszewska A, Zindamoyen A, Banker A, Serhiienko A, Loo A, Meireles A, Aydin B, Luebke B, Özmen C, Odrobina D, Bertelli E, Unsal E, Kenneth F, Becquet F, Hamon F, Pellegrini G, Tosi G, Donvito G, Khaqan H, Badat I, Fiser I, Michalewski J, Le Rouic J, Nawrocki J, Zarallo-Gallardo J, Lee J, Boninska K, Nowomiejska K, Dziegielewski K, Arrevola L, Lytvynchuk L, Elshafei M, Pietras-Trzpiel M, Irós M, Detjen M, Iglicki M, Badino M, Angelina M, Gavura M, Hasanreisoğlu M, Karadaş M, Atienza N, Acar N, Okonkwo O, Miesbauer P, Malgorzata P, Velez-Montoya R, Robert R, Frisina R, Soyeur R, Rejdak R, Giannini R, Mittal S, Saidkasimova S, Abdulsalam S, Cisiecki S, Rusnak S, Teoh S, Teixeira S, Altan T, Schrader W, Kapran Z, Aktas Z, Szijártó Z. International Practice Patterns for the Management of Acute Postsurgical and Postintravitreal Injection Endophthalmitis European Vitreo-Retinal Society Endophthalmitis Study Report 1. Ophthalmology Retina 2019, 3: 461-467. PMID: 31043364, DOI: 10.1016/j.oret.2019.03.009.Peer-Reviewed Original ResearchMeSH KeywordsAgedAngiogenesis InhibitorsAnti-Bacterial AgentsAntibiotic ProphylaxisCataract ExtractionDisease ManagementEndophthalmitisEuropeEye Infections, BacterialFemaleFollow-Up StudiesHumansIncidenceIntravitreal InjectionsMaleMiddle AgedOphthalmologyPractice Guidelines as TopicRetrospective StudiesSocieties, MedicalSurgical Wound InfectionVitrectomyConceptsEarly pars plana vitrectomyPars plana vitrectomyIntravitreal injectionIntravitreal antibioticsAcute endophthalmitisPlana vitrectomyIntraocular surgeryCataract surgeryPractice patternsAbsence of endophthalmitisSecond intravitreal injectionSecondary lens implantationProportion of eyesInternational practice patternsAcute postoperativeSystemic steroidsIntravitreal steroidsLens implantationAdjunctive therapySystemic antibioticsPostinjection endophthalmitisMulticenter studyRetina specialistsTherapeutic regimensVitreous opacification
2013
Incidence and Management of Elevated Intraocular Pressure with Antivascular Endothelial Growth Factor Agents
Abedi G, Adelman RA, Salim S. Incidence and Management of Elevated Intraocular Pressure with Antivascular Endothelial Growth Factor Agents. Seminars In Ophthalmology 2013, 28: 126-130. PMID: 23631423, DOI: 10.3109/08820538.2013.771195.Peer-Reviewed Original ResearchConceptsPersistent ocular hypertensionIntraocular pressureOcular hypertensionIntravitreal antivascular endothelial growth factorAntivascular endothelial growth factor agentsChronic intraocular pressure elevationEndothelial growth factor agentsIntravitreal anti-VEGF injectionsAntivascular endothelial growth factorAnti-VEGF injectionsGrowth factor agentsIntraocular pressure elevationElevated intraocular pressureElectronic literature searchEndothelial growth factorKey search termsFactor agentsPrompt diagnosisVEGF injectionAcute elevationIntravitreal injectionIOP elevationPersistent elevationPressure elevationGlaucomatous eyes
2012
Effects of Music Therapy on Intravitreal Injections: A Randomized Clinical Trial
Chen X, Seth RK, Rao VS, Huang JJ, Adelman RA. Effects of Music Therapy on Intravitreal Injections: A Randomized Clinical Trial. Journal Of Ocular Pharmacology And Therapeutics 2012, 28: 414-419. PMID: 22506884, DOI: 10.1089/jop.2011.0257.Peer-Reviewed Original ResearchConceptsMusic therapy groupIntravitreal injectionTherapy groupControl groupOutpatient settingClinical trialsMusic therapyFuture injectionsRandomized clinical trialsMain outcome measuresPost-procedure questionnaireSpielberger State-Trait Anxiety InventorySTAI-S scoresState-Trait Anxiety InventoryTrait Anxiety InventoryRetina clinicMost patientsPain QuestionnaireSafe interventionSubjective painOutcome measuresPatientsPainTherapyGreater decrease
2010
Persistent Ocular Hypertension Following Intravitreal Bevacizumab and Ranibizumab Injections
Adelman RA, Zheng Q, Mayer HR. Persistent Ocular Hypertension Following Intravitreal Bevacizumab and Ranibizumab Injections. Journal Of Ocular Pharmacology And Therapeutics 2010, 26: 105-110. PMID: 20187807, DOI: 10.1089/jop.2009.0076.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overAntibodies, MonoclonalAntibodies, Monoclonal, HumanizedBevacizumabDrug Administration ScheduleDrug Therapy, CombinationFemaleHumansInjections, IntraocularIntraocular PressureMacular DegenerationMaleOcular HypertensionRanibizumabRetrospective StudiesTime FactorsVascular Endothelial Growth Factor AVitreous BodyConceptsAge-related macular degenerationPersistent ocular hypertensionOcular hypertensionIntraocular pressureIntravitreal bevacizumabRanibizumab injectionsIntravitreal injectionPrevious diagnosisGlaucoma/ocular hypertensionIntravitreal anti-VEGF injectionsAnti-VEGF injectionsIntravitreal bevacizumab injectionPostinjection intraocular pressurePreinjection intraocular pressureMultiple intravitreal injectionsTertiary referral centerRetrospective case seriesElevated intraocular pressureBevacizumab injectionIntravitreal ranibizumabReferral centerCase seriesVEGF injectionIOP increaseYAG capsulotomy
2009
ASSESSMENT OF OPTIC NERVE CUP-TO-DISK RATIO CHANGES IN PATIENTS RECEIVING MULTIPLE INTRAVITREAL INJECTIONS OF ANTIVASCULAR ENDOTHELIAL GROWTH FACTOR AGENTS
SETH RK, SALIM S, SHIELDS MB, ADELMAN RA. ASSESSMENT OF OPTIC NERVE CUP-TO-DISK RATIO CHANGES IN PATIENTS RECEIVING MULTIPLE INTRAVITREAL INJECTIONS OF ANTIVASCULAR ENDOTHELIAL GROWTH FACTOR AGENTS. Retina 2009, 29: 956-959. PMID: 19584654, DOI: 10.1097/iae.0b013e3181a91dfd.Peer-Reviewed Original ResearchMeSH KeywordsAntibodies, MonoclonalAntibodies, Monoclonal, HumanizedAptamers, NucleotideDrug Therapy, CombinationEyeFollow-Up StudiesFundus OculiHumansInjectionsIntraocular PressureOptic DiskOptic NerveRanibizumabRegional Blood FlowRetrospective StudiesSingle-Blind MethodVascular Endothelial Growth Factor AVitreous BodyConceptsMultiple intravitreal injectionsAnti-VEGF agentsIntraocular pressure riseIntraocular pressure fluctuationIntravitreal injectionMean changeControl groupTransient intraocular pressure riseSignificant differencesDisc ratio changesOptic nerve cupHistory of glaucomaAdditional prospective studiesGrowth factor effectsFellow eyesGlaucoma specialistsOptic nerveProspective studyOptic disc imagesFundus photographsTriamcinolone acetonideInclusion criteriaDisc ratioVertical cupPatients
2008
Are intravitreal bevacizumab and ranibizumab effective in a rat model of choroidal neovascularization?
Lu F, Adelman RA. Are intravitreal bevacizumab and ranibizumab effective in a rat model of choroidal neovascularization? Graefe's Archive For Clinical And Experimental Ophthalmology 2008, 247: 171. PMID: 18781316, DOI: 10.1007/s00417-008-0936-y.Peer-Reviewed Original ResearchMeSH KeywordsAngiogenesis InhibitorsAnimalsAntibodies, MonoclonalAntibodies, Monoclonal, HumanizedAptamers, NucleotideBevacizumabChoroidal NeovascularizationDisease Models, AnimalDose-Response Relationship, DrugFluorescein AngiographyInjectionsLight CoagulationMacular DegenerationRanibizumabRatsRats, Inbred BNVascular Endothelial Growth Factor AVitreous BodyConceptsLeakage of CNVTreatment of CNVPegaptanib sodiumChoroidal neovascularizationIntravitreal injectionRat modelBackgroundVascular endothelial growth factorAnti-VEGF agentsEffect of bevacizumabAnti-VEGF medicationsBrown Norway ratsEndothelial growth factorNon-human primatesAngiography 1Histopathologic toxicityIntravitreal bevacizumabCNV leakageFluorescein angiographyLaser photocoagulationBevacizumabTherapeutic effectCNV lesionsRanibizumabDay 1Important stimulator
2007
Choroidal Neovascularization Associated with West Nile Virus Chorioretinitis
Seth RK, Stoessel KM, Adelman RA. Choroidal Neovascularization Associated with West Nile Virus Chorioretinitis. Seminars In Ophthalmology 2007, 22: 81-84. PMID: 17564926, DOI: 10.1080/08820530701418375.Peer-Reviewed Original ResearchConceptsWest Nile virus chorioretinitisChoroidal neovascularizationChoroidal Neovascularization AssociatedLate-onset complicationsBest therapeutic optionGood anatomical responseNeovascularization AssociatedDiabetes mellitusLeft eyeIntravitreal injectionTherapeutic optionsChorioretinitisNeovascularizationBevacizumabPatientsInjectionMellitusComplicationsBaseline