2024
Testing the feasibility, acceptability, and preliminary efficacy of integrating accommodation strategies into an HIV prevention intervention for people who inject drugs with cognitive dysfunction
Mistler C, Shrestha R, Copenhaver M. Testing the feasibility, acceptability, and preliminary efficacy of integrating accommodation strategies into an HIV prevention intervention for people who inject drugs with cognitive dysfunction. Journal Of Substance Use And Addiction Treatment 2024, 169: 209582. PMID: 39551147, DOI: 10.1016/j.josat.2024.209582.Peer-Reviewed Original ResearchHIV prevention interventionsOpioid use disorderBehavioral HIV prevention interventionHIV prevention informationPreventive interventionsCognitive profile of individualsIntervention contentActive control conditionPrevention informationPreliminary efficacyControl conditionEnhanced HIV prevention interventionPreventive intervention conditionHIV risk reduction informationProfile of individualsHIV-related risk behaviorsRisk of HIVRisk reduction skillsAccommodation strategiesRisk reduction informationPre-exposure prophylaxisCognitive profileUse disorderCognitive dysfunctionIntervention conditionT73 Application of the Multiphase Optimization Strategy (MOST) to Optimize HIV Prevention Targeting People on Medication for Opioid Use Disorder (MOUD) who Have Cognitive Dysfunction: A Study Protocol
Copenhaver M, Mistler C, Shrestha R. T73 Application of the Multiphase Optimization Strategy (MOST) to Optimize HIV Prevention Targeting People on Medication for Opioid Use Disorder (MOUD) who Have Cognitive Dysfunction: A Study Protocol. Drug And Alcohol Dependence 2024, 260: 110522. DOI: 10.1016/j.drugalcdep.2023.110522.Peer-Reviewed Original Research
2023
Application of the multiphase optimisation strategy (MOST) to optimise HIV prevention targeting people on medication for opioid use disorder (MOUD) who have cognitive dysfunction: protocol for a MOST study
Mistler C, Shrestha R, Gunstad J, Collins L, Madden L, Huedo-Medina T, Sibilio B, Copenhaver N, Copenhaver M. Application of the multiphase optimisation strategy (MOST) to optimise HIV prevention targeting people on medication for opioid use disorder (MOUD) who have cognitive dysfunction: protocol for a MOST study. BMJ Open 2023, 13: e071688. PMID: 37399447, PMCID: PMC10314648, DOI: 10.1136/bmjopen-2023-071688.Peer-Reviewed Original ResearchConceptsOpioid use disorderMultiphase optimization strategyCognitive dysfunctionHIV preventionUse disordersPromising biomedical interventionsPre-exposure prophylaxisHIV incidence ratesHIV risk reductionHIV prevention interventionsDrug treatment settingsInstitutional review boardInformed consent formPrEP adherenceHIV prevention contentHIV infectionPrEP uptakeStudy protocolIncidence rateRisk groupsPrevention interventionsPWIDTreatment settingsReview boardEffective interventions
2021
Adapting behavioural interventions to compensate for cognitive dysfunction in persons with opioid use disorder
Mistler CB, Shrestha R, Gunstad J, Sanborn V, Copenhaver MM. Adapting behavioural interventions to compensate for cognitive dysfunction in persons with opioid use disorder. General Psychiatry 2021, 34: e100412. PMID: 34504995, PMCID: PMC8370499, DOI: 10.1136/gpsych-2020-100412.Peer-Reviewed Original ResearchCognitive profileBehavioral interventionsCognitive dysfunctionAccommodation strategiesSimilar cognitive profileUse disordersFuture intervention researchSuch behavioral interventionsCognitive demandsExecutive functionBehavioral therapyCognitive functionInformation processingIntervention approachesIntervention researchIntervention placePatient's abilityOpioid use disorderInterventionTreatment outcomesPsychoeducationDisordersResearchMemoryAbilityDeveloping a cognitive dysfunction risk score for use with opioid-dependent persons in drug treatment
Copenhaver MM, Sanborn V, Shrestha R, Mistler CB, Sullivan MC, Gunstad J. Developing a cognitive dysfunction risk score for use with opioid-dependent persons in drug treatment. Drug And Alcohol Dependence 2021, 224: 108726. PMID: 33930640, PMCID: PMC8180490, DOI: 10.1016/j.drugalcdep.2021.108726.Peer-Reviewed Original ResearchConceptsMild cognitive impairmentCognitive dysfunctionRisk scoreDrug treatmentPredictors of MCIOpioid-dependent personsOpioid use disorderPredictive risk scoreMedical chart dataNeuro-cognitive impairmentResource-limited settingsChart dataDrug treatment facilitiesAddiction-related servicesLarger validation studiesPatient demographicsROC curve areaUse disordersTreatment engagementCognitive impairmentPatientsOptimal cutClinical settingLogistic regressionMCI cases
2020
Association between the brief inventory of neurocognitive impairment (BINI) and objective cognitive testing among persons with opioid use disorders in drug treatment
Copenhaver MM, Sanborn V, Shrestha R, Mistler C, Gunstad J. Association between the brief inventory of neurocognitive impairment (BINI) and objective cognitive testing among persons with opioid use disorders in drug treatment. Journal Of Addictive Diseases 2020, 39: 166-174. PMID: 33047651, PMCID: PMC11395862, DOI: 10.1080/10550887.2020.1831129.Peer-Reviewed Original ResearchConceptsMethadone maintenance therapyDrug treatmentNeurocognitive dysfunctionNeurocognitive impairmentOpioid use disorderPossible clinical utilityAccommodation of patientsNIH ToolboxSubjective cognitive dysfunctionMaintenance therapyObjective cognitive testingSpecific neurocognitive profileTreatment outcomesCognitive dysfunctionClinical utilityUse disordersBrief inventoryObjective test performanceDysfunctionCognitive testingCutoff scoreNeurocognitive profileTest batteryObjective performanceImpairment