Improvements in circulating levels of immune-reactive proteins simultaneous with depression of thymus-dependent lymphocytes during radiation therapy for solid malignancies
Baskies A, Chretien P, Weiss J, Makuch R, Spiegel H. Improvements in circulating levels of immune-reactive proteins simultaneous with depression of thymus-dependent lymphocytes during radiation therapy for solid malignancies. International Journal Of Radiation Oncology • Biology • Physics 1979, 5: 67-68. DOI: 10.1016/0360-3016(79)91047-2.Peer-Reviewed Original ResearchThymus-dependent lymphocytesSolid malignanciesRadiation therapyImmune-reactive proteinsMalignancyLymphocytesTherapyThymosin immunotherapy in patients with small cell carcinoma of the lung. Correlation of in vitro studies with clinical course
Lipson S, Chretien P, Makuch R, Kenady D, Cohen M. Thymosin immunotherapy in patients with small cell carcinoma of the lung. Correlation of in vitro studies with clinical course. Cancer 1979, 43: 863-870. PMID: 218717, DOI: 10.1002/1097-0142(197903)43:3<863::aid-cncr2820430313>3.0.co;2-5.Peer-Reviewed Original ResearchConceptsTotal T cellsPretreatment CEA levelsT cellsCEA levelsClinical courseCellular immunityTumor responsePretreatment levelsCarcinoembryonic antigenAdministration of thymosinIntensive chemotherapy programsPeripheral blood levelsSmall cell carcinomaDuration of responseOverall tumor responseThymus-dependent lymphocytesLarger patient populationType of treatmentP groupMechanism of actionComplete remissionT60 groupChemotherapy programBronchogenic carcinomaImmune defects