Interictal spikes on intracranial recording: Behavior, physiology, and implications
Spencer SS, Goncharova II, Duckrow RB, Novotny EJ, Zaveri HP. Interictal spikes on intracranial recording: Behavior, physiology, and implications. Epilepsia 2008, 49: 1881-1892. PMID: 18479398, DOI: 10.1111/j.1528-1167.2008.01641.x.Peer-Reviewed Original ResearchMeSH KeywordsAdultAnticonvulsantsBrainCombined Modality TherapyEpilepsyHumansMagnetic Resonance ImagingNeurosurgical ProceduresPositron-Emission TomographyTomography, Emission-Computed, Single-PhotonConceptsInterictal spikesAED withdrawalSeizure onsetSpike rateMedial temporal lobe seizuresAntiepileptic drug changesRefractory epileptic patientsTemporal lobe seizuresOnset seizuresDrug changesEpileptic patientsNeocortical locationsClinical meaningMedial temporalSeizuresIntracranial electrodesDays of recordingAED mechanismsIntracranial recordingsSignificant increaseAEDsPrevious reportsOnsetSpecific effectsWithdrawal