2008
Interictal spikes on intracranial recording: Behavior, physiology, and implications
Spencer SS, Goncharova II, Duckrow RB, Novotny EJ, Zaveri HP. Interictal spikes on intracranial recording: Behavior, physiology, and implications. Epilepsia 2008, 49: 1881-1892. PMID: 18479398, DOI: 10.1111/j.1528-1167.2008.01641.x.Peer-Reviewed Original ResearchConceptsInterictal spikesAED withdrawalSeizure onsetSpike rateMedial temporal lobe seizuresAntiepileptic drug changesRefractory epileptic patientsTemporal lobe seizuresOnset seizuresDrug changesEpileptic patientsNeocortical locationsClinical meaningMedial temporalSeizuresIntracranial electrodesDays of recordingAED mechanismsIntracranial recordingsSignificant increaseAEDsPrevious reportsOnsetSpecific effectsWithdrawal
1992
Regional coherence and the transfer of ictal activity during seizure onset in the medial temporal lobe
Duckrow R, Spencer S. Regional coherence and the transfer of ictal activity during seizure onset in the medial temporal lobe. Clinical Neurophysiology 1992, 82: 415-422. PMID: 1375548, DOI: 10.1016/0013-4694(92)90046-k.Peer-Reviewed Original ResearchConceptsMedial temporal lobeSeizure onsetTemporal lobeBrain regionsSustained seizure activityHippocampal depth electrodesHuman medial temporal lobeConsecutive patientsResective surgerySeizure dischargesSeizure activityEpileptiform activityIctal activityPosterior hippocampusDepth electrodesNeuronal entrainmentTransient increaseIctal periodNeuronal synchronizationPossible resective surgeryEEG activityOnsetLobeAdjacent contactsSec epochs