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Treatment of Severe Metabolic Alkalosis in a Patient With Congestive Heart Failure
Peixoto AJ, Alpern RJ. Treatment of Severe Metabolic Alkalosis in a Patient With Congestive Heart Failure. American Journal Of Kidney Diseases 2013, 61: 822-827. PMID: 23481366, DOI: 10.1053/j.ajkd.2012.10.028.Peer-Reviewed Original ResearchConceptsCongestive heart failureHeart failureMetabolic alkalosisLow bicarbonate dialysisRenal bicarbonate excretionRenin-angiotensin systemSevere metabolic alkalosisDistal sodium deliveryCommon acid-base disorderAcid-base disordersDiuretic regimenDiuretic therapyAldosterone antagonistsNeurohormonal activationCirculatory failureBicarbonate excretionKidney failurePotassium repletionSodium deliveryBase excessUrine acidificationAppropriate managementAlkalosisDisease statesBicarbonate retentionChapter 58 Clinical Syndromes of Metabolic Alkalosis
Moe O, Alpern R, Seldin D. Chapter 58 Clinical Syndromes of Metabolic Alkalosis. 2013, 2021-2047. DOI: 10.1016/b978-0-12-381462-3.00058-6.Peer-Reviewed Original Research
1997
Metabolic alkalosis.
Palmer BF, Alpern RJ. Metabolic alkalosis. Journal Of The American Society Of Nephrology 1997, 8: 1462-9. PMID: 9294840, DOI: 10.1681/asn.v891462.Peer-Reviewed Original Research
1991
Dietary NaCl modulates Na(+)-H+ antiporter activity in renal cortical apical membrane vesicles
Moe OW, Tejedor A, Levi M, Seldin DW, Preisig PA, Alpern RJ. Dietary NaCl modulates Na(+)-H+ antiporter activity in renal cortical apical membrane vesicles. American Journal Of Physiology 1991, 260: f130-f137. PMID: 1847012, DOI: 10.1152/ajprenal.1991.260.1.f130.Peer-Reviewed Original ResearchConceptsDietary NaClNaCl reabsorptionSystemic acid-base disturbancesExtracellular fluid volume depletionNaHCO3 reabsorptionExtracellular fluid volume expansionFluid volume depletionHigh-salt dietChronic metabolic alkalosisFluid volume expansionAcridine orange fluorescence methodExtracellular fluid volumeAcid-base disturbancesAntiporter activityDietary protocolChronic alterationsVolume depletionMetabolic alkalosisChronic changesHS dietApical membrane vesiclesLS dietFluid volumeRatsReabsorption