2005
Molecular Biology of Renal Acid–Base Transporters
Moe O, Baum M, Alpern R. Molecular Biology of Renal Acid–Base Transporters. 2005, 141-198. DOI: 10.1201/b14402-9.Peer-Reviewed Original ResearchAcid-base transportersProtein of interestClassical protein chemistryRecombinant DNA techniquesFunctional complementationMammalian cellsRegulatory proteinsRegulatory mechanismsWhole organismIndividual transportersMembrane vesiclesDNA techniquesMolecular biologyHigh abundanceProtein chemistryXenopus oocytesMolecular definitionTransportersProteinCurrent knowledgeCell culturesIndividual nephron segmentsAcid-base balanceComplementationCloning
1995
Molecular cloning of ion transporters: potential clinical implications.
Cano A, Alpern R. Molecular cloning of ion transporters: potential clinical implications. Seminars In Nephrology 1995, 15: 2-8. PMID: 7754253.Peer-Reviewed Original ResearchConceptsIon transportersIntegral membrane proteinsStructure/functionUnderstanding of functionMembrane proteinsMolecular cloningTransporter proteinsHereditary ovalocytosisProteinHyperkalemic periodic paralysisCloningGenetic disordersTransportersMyotonia congenitaMultiple levelsAbnormal structurePotential clinical implicationsPeriodic paralysisEnzymeHereditary spherocytosisRegulationOvalocytosisCystic fibrosisFunction