Insights From Invasive Cardiopulmonary Exercise Testing of Patients With Myalgic Encephalomyelitis/Chronic Fatigue Syndrome
Joseph P, Arevalo C, Oliveira RKF, Faria-Urbina M, Felsenstein D, Oaklander AL, Systrom DM. Insights From Invasive Cardiopulmonary Exercise Testing of Patients With Myalgic Encephalomyelitis/Chronic Fatigue Syndrome. CHEST Journal 2021, 160: 642-651. PMID: 33577778, PMCID: PMC8727854, DOI: 10.1016/j.chest.2021.01.082.Peer-Reviewed Original ResearchConceptsSmall fiber neuropathyRight atrial pressurePostural orthostatic tachycardiaMyalgic encephalomyelitis/chronic fatigue syndromeCardiopulmonary exercise testingChronic fatigue syndromeExertional intoleranceExercise testingFatigue syndromeControl subjectsOxygen extractionInvasive cardiopulmonary exercise testingLow right atrial pressureME/CFS criteriaHigh pulmonary blood flowME/CFS patientsPeripheral oxygen extractionSmall fiber pathologyPulmonary blood flowSystemic oxygen extractionCardiac returnIntrinsic heartNeurovascular dysregulationRight shuntingCFS patients