2007
c-Jun NH2-Terminal Kinase 2 Inhibits Gamma Interferon Production during Anaplasma phagocytophilum Infection
Pedra JH, Mattner J, Tao J, Kerfoot SM, Davis RJ, Flavell RA, Askenase PW, Yin Z, Fikrig E. c-Jun NH2-Terminal Kinase 2 Inhibits Gamma Interferon Production during Anaplasma phagocytophilum Infection. Infection And Immunity 2007, 76: 308-316. PMID: 17998313, PMCID: PMC2223674, DOI: 10.1128/iai.00599-07.Peer-Reviewed Original ResearchConceptsIFN-gamma productionA. phagocytophilum infectionPhagocytophilum infectionIFN-gammaJnk2-null miceNatural killer T cellsA. phagocytophilumKiller T cellsIFN-gamma releaseIFN-gamma secretionGamma interferon productionT cell agonistsAnaplasma phagocytophilum infectionT cellsEarly eradicationGamma interferonInterferon productionInfectionC-Jun NH2-terminal kinase-2Inhibitory effectElevated levelsMiceAnaplasma phagocytophilumPhagocytophilumKinase 2
1999
C-C chemokines in allergen-induced late-phase cutaneous responses in atopic subjects: association of eotaxin with early 6-hour eosinophils, and of eotaxin-2 and monocyte chemoattractant protein-4 with the later 24-hour tissue eosinophilia, and relationship to basophils and other C-C chemokines (monocyte chemoattractant protein-3 and RANTES).
Ying S, Robinson D, Meng Q, Barata L, McEuen A, Buckley M, Walls A, Askenase P, Kay A. C-C chemokines in allergen-induced late-phase cutaneous responses in atopic subjects: association of eotaxin with early 6-hour eosinophils, and of eotaxin-2 and monocyte chemoattractant protein-4 with the later 24-hour tissue eosinophilia, and relationship to basophils and other C-C chemokines (monocyte chemoattractant protein-3 and RANTES). The Journal Of Immunology 1999, 163: 3976-84. PMID: 10491000, DOI: 10.4049/jimmunol.163.7.3976.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAllergensBasophilsCell MovementChemokine CCL11Chemokine CCL24Chemokine CCL5Chemokine CCL7Chemokines, CCCytokinesDermatitis, AtopicEosinophiliaEosinophilsHumansImmunophenotypingMiddle AgedMonocyte Chemoattractant ProteinsReceptors, CCR3Receptors, ChemokineRNA, MessengerTime FactorsConceptsMonocyte chemoattractant protein-3C-C chemokinesEotaxin-2MCP-4T cellsAtopic subjectsLate-phase cutaneous responseCD4+ T cellsEotaxin receptor CCR3Human atopic subjectsMonocyte chemoattractant protein-4CD3+ cellsCD68+ macrophagesEG2+ eosinophilsExpression of eotaxinCCR3+ cellsMCP-4 mRNAElastase+ neutrophilsLate eosinophiliaAllergic tissue reactionsEotaxin proteinCD3+Allergen-inducedRelationship of expressionEotaxin mRNA