2007
Shared features in the pathobiology of babesiosis and malaria
Krause PJ, Daily J, Telford SR, Vannier E, Lantos P, Spielman A. Shared features in the pathobiology of babesiosis and malaria. Trends In Parasitology 2007, 23: 605-610. PMID: 17988944, DOI: 10.1016/j.pt.2007.09.005.Peer-Reviewed Original ResearchConceptsPlasmodium falciparum infectionPathogenesis of babesiosisFulminant diseaseClinical courseFalciparum infectionSimilar pathogenesisCytokine activationHealth problemsIntraerythrocytic protozoaMalariaPathobiologyContinued investigationPathogenesisBabesiosisDiseaseRecent studiesHumansInfectionImportant diseaseCytoadherenceSerum Reactivity against Borrelia burgdorferi OspA in Patients with Rheumatoid Arthritis▿
Hsieh YF, Liu HW, Hsu TC, Wei J, Shih CM, Krause PJ, Tsay GJ. Serum Reactivity against Borrelia burgdorferi OspA in Patients with Rheumatoid Arthritis▿. MSphere 2007, 14: 1437-1441. PMID: 17881508, PMCID: PMC2168181, DOI: 10.1128/cvi.00151-07.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAged, 80 and overAntibodies, BacterialAntigens, BacterialAntigens, SurfaceArthritis, RheumatoidAutoimmune DiseasesBacterial Outer Membrane ProteinsBacterial VaccinesBlotting, WesternBorrelia burgdorferiEnzyme-Linked Immunosorbent AssayFemaleHumansLipoproteinsLyme DiseaseMaleMiddle AgedRecombinant Fusion ProteinsConceptsRheumatoid arthritis patientsRheumatoid arthritisOspA antigenArthritis patientsAutoimmune diseasesSerum reactivityLyme diseaseDisease Activity ScoreCommon clinical featuresLyme disease patientsSurface protein AArthritis correlatesSynovial histologyOuter surface protein ALyme arthritisActivity scoreClinical featuresDisease patientsSerum concentrationsSimilar pathogenesisHealthy subjectsPatientsArthritisDisease severityDisease
2006
Absence of erythrocyte sequestration in a case of babesiosis in a splenectomized human patient
Clark IA, Budd AC, Hsue G, Haymore BR, Joyce AJ, Thorner R, Krause PJ. Absence of erythrocyte sequestration in a case of babesiosis in a splenectomized human patient. Malaria Journal 2006, 5: 69. PMID: 16887045, PMCID: PMC1552079, DOI: 10.1186/1475-2875-5-69.Peer-Reviewed Original ResearchConceptsMulti-organ failureParasitized erythrocytesSevere multi-organ failureBabesia microti infectionChronic lymphocytic leukemiaCases of babesiosisFalciparum malariaSplenectomized patientsSimilar pathogenesisVascular occlusionMicroti infectionErythrocyte sequestrationLymphocytic leukemiaProtozoal infectionsVascular locationColon cancerHuman patientsResultsNo evidenceVascular lumenHuman casesB. microtiTissue sectionsPatientsPathogenesisInfection