2024
Tafenoquine for Relapsing Babesiosis: A Case Series
Krause P, Rogers R, Shah M, Kang H, Parsonnet J, Kodama R, Vannier E. Tafenoquine for Relapsing Babesiosis: A Case Series. Clinical Infectious Diseases 2024, 79: 130-137. PMID: 38814096, PMCID: PMC11259219, DOI: 10.1093/cid/ciae238.Peer-Reviewed Original ResearchRelapsing babesiosisPolymerase chain reactionReal-time polymerase chain reactionImmunocompromised patientsTreatment of Plasmodium vivax malariaPlasmodium vivax malariaModel of acute infectionAntimicrobial agentsBlood smearsAnimal models of acute infectionsWeekly maintenance dosesAcquisition of resistanceAtovaquone-proguanilVivax malariaMalaria prophylaxisMaintenance doseLoading doseCase seriesDelayed clearanceAcute infectionTafenoquinePrevent relapseThin blood smearsLow dosesAnimal models
2020
Parasite burden and red blood cell exchange transfusion for babesiosis
O'Bryan J, Gokhale A, Hendrickson JE, Krause PJ. Parasite burden and red blood cell exchange transfusion for babesiosis. Journal Of Clinical Apheresis 2020, 36: 127-134. PMID: 33179803, PMCID: PMC9517950, DOI: 10.1002/jca.21853.Peer-Reviewed Original ResearchConceptsEnd-organ dysfunctionPeak parasitemia levelsRed blood cell exchange transfusionParasitemia levelsExchange transfusionPeak parasitemiaDisease severityParasite burdenYale-New Haven HospitalBabesia microti parasitemiaHigh-grade parasitemiaRetrospective chart reviewBabesia microti infectionNew Haven HospitalAntimicrobial agentsChart reviewHepatic dysfunctionPatient demographicsClinical statusMedian lengthLaboratory indicatorsMicroti infectionDegree of hemolysisNineteen subjectsDysfunctionClofazimine, a Promising Drug for the Treatment of Babesia microti Infection in Severely Immunocompromised Hosts
Tuvshintulga B, Vannier E, Tayebwa DS, Gantuya S, Sivakumar T, Guswanto A, Krause PJ, Yokoyama N, Igarashi I. Clofazimine, a Promising Drug for the Treatment of Babesia microti Infection in Severely Immunocompromised Hosts. The Journal Of Infectious Diseases 2020, 222: 1027-1036. PMID: 32310272, DOI: 10.1093/infdis/jiaa195.Peer-Reviewed Original ResearchConceptsB. microti parasitesMicroti infectionHigh-grade parasitemiaDrug-resistant tuberculosisB. microtiBabesia microti infectionAdditional preclinical studiesB. microti infectionImmunocompromised hostB. microti DNAPolymerase chain reactionPreclinical studiesIncidence of babesiosisPromising drugRadical cureMinimal doseClofazimineDay 10Blood smearsBabesia microtiNovel drugsParasitemiaChain reactionMicroscopic examinationAntimicrobial agents
1994
Quality Standard for Antimicrobial Prophylaxis in Surgical Procedures
Dellinger E, Gross P, Barrett T, Krause P, Martone W, McGowan J, Sweet R, Wenzel R. Quality Standard for Antimicrobial Prophylaxis in Surgical Procedures. Infection Control And Hospital Epidemiology 1994, 15: 182-188. DOI: 10.2307/30145558.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsPostoperative wound infectionProphylactic antimicrobial agentsInfectious Diseases SocietyDiseases SocietyWound infectionProphylactic antibioticsReliable administrationPediatric Infectious Diseases SocietyAntimicrobial agentsInfectious diseasesQuality Standards SubcommitteeSurgical infectious diseasesSurgical Infection SocietyClinical Affairs CommitteeMethod of administrationAntimicrobial prophylaxisPostoperative infectionPotential morbidityOperative procedureHospital epidemiologySurgical proceduresInfection controlOptimal doseApparent efficacyDrug AdministrationQuality standard for antimicrobial prophylaxis in surgical procedures. The Infectious Diseases Society of America.
Dellinger E, Gross P, Barrett T, Krause P, Martone W, McGowan J, Sweet R, Wenzel R. Quality standard for antimicrobial prophylaxis in surgical procedures. The Infectious Diseases Society of America. Infection Control And Hospital Epidemiology 1994, 15: 182-8. PMID: 8207176, DOI: 10.1086/646887.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsInfectious Diseases SocietyPostoperative wound infectionProphylactic antimicrobial agentsDiseases SocietyWound infectionProphylactic antibioticsReliable administrationPediatric Infectious Diseases SocietyAntimicrobial agentsInfectious diseasesQuality Standards SubcommitteeSurgical infectious diseasesSurgical Infection SocietyClinical Affairs CommitteeMethod of administrationAntimicrobial prophylaxisPostoperative infectionPotential morbidityHospital epidemiologyOperative procedureSurgical proceduresOptimal doseApparent efficacyDrug AdministrationOptimal durationQuality Standard for Antimicrobial Prophylaxis in Surgical Procedures
Dellinger E, Gross P, Barrett T, Krause P, Martone W, McGowan J, Sweet R, Wenzel R. Quality Standard for Antimicrobial Prophylaxis in Surgical Procedures. Clinical Infectious Diseases 1994, 18: 422-427. PMID: 8011827, DOI: 10.1093/clinids/18.3.422.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsPostoperative wound infectionProphylactic antimicrobial agentsInfectious Diseases SocietyDiseases SocietyWound infectionProphylactic antibioticsReliable administrationPediatric Infectious Diseases SocietyAntimicrobial agentsInfectious diseasesQuality Standards SubcommitteeSurgical infectious diseasesSurgical Infection SocietyClinical Affairs CommitteeMethod of administrationPostoperative infectionPotential morbidityHospital epidemiologyOperative procedureInfection controlOptimal doseApparent efficacyDrug AdministrationOptimal durationHospital pharmacists