2024
Absence of Anti-Babesia microti antibody in commercial intravenous immunoglobulin (IVIG)
Kostka J, Maharjan A, Kumar S, Hackenyos D, Krause P, Dieckhaus K. Absence of Anti-Babesia microti antibody in commercial intravenous immunoglobulin (IVIG). PLOS Neglected Tropical Diseases 2024, 18: e0012035. PMID: 38484010, PMCID: PMC10965045, DOI: 10.1371/journal.pntd.0012035.Peer-Reviewed Original ResearchConceptsIntravenous immunoglobulinB. microti antibodiesBabesiosis patientsSpectrum of disease severityCommercial intravenous immunoglobulinEffective treatment strategiesSevere organ damageHost antibody responseImmunocompromised patientsAdjunctive therapyOrgan damageTreatment strategiesAcute andClinical trialsMicroti antibodiesAsymptomatic infectionAntibody responseTherapeutic benefitTherapeutic effectPatientsDisease severityAntibodiesImmunofluorescence assayProtozoan infectionsCommercial samples
2006
Confirmation of Tick Bite by Detection of Antibody to Ixodes Calreticulin Salivary Protein▿
Alarcon-Chaidez F, Ryan R, Wikel S, Dardick K, Lawler C, Foppa IM, Tomas P, Cushman A, Hsieh A, Spielman A, Bouchard KR, Dias F, Aslanzadeh J, Krause PJ. Confirmation of Tick Bite by Detection of Antibody to Ixodes Calreticulin Salivary Protein▿. MSphere 2006, 13: 1217-1222. PMID: 16928887, PMCID: PMC1656538, DOI: 10.1128/cvi.00201-06.Peer-Reviewed Original ResearchConceptsEnzyme-linked immunosorbent assayImmune responseTick exposureBALB/c miceC3H/HeNTick-borne infectionsHuman granulocytic anaplasmosisDetection of antibodiesLaboratory markersAntibody responseC miceTick biteSalivary proteinsObjective evidenceLyme diseaseImmunosorbent assayGranulocytic anaplasmosisHuman babesiosisSalivary glandsIxodes ticksAntibodiesBlood mealSame assayMiceSerum
2003
Babesiosis Diagnosis and Treatment
Krause PJ. Babesiosis Diagnosis and Treatment. Vector-Borne And Zoonotic Diseases 2003, 3: 45-51. PMID: 12804380, DOI: 10.1089/153036603765627451.Peer-Reviewed Original ResearchConceptsBlood smearsThin blood smearsPolymerase chain reactionRobust antibody responseLife-saving therapyUseful screening testPulmonary compromiseSubclinical illnessSerologic testingClinical manifestationsExchange transfusionAntibody responseAdverse reactionsHigh parasitemiaConclusive diagnosisSevere diseaseAccurate diagnosisScreening testBabesial infectionBabesia microtiHuman babesiosisInfectionSignificant hemolysisDiseaseSmears