2002
Renal expression of novel Na+/H+exchanger isoform NHE8
Goyal S, Heuvel G, Aronson PS. Renal expression of novel Na+/H+exchanger isoform NHE8. American Journal Of Physiology. Renal Physiology 2002, 284: f467-f473. PMID: 12409279, DOI: 10.1152/ajprenal.00352.2002.Peer-Reviewed Original ResearchMeSH KeywordsAmino Acid SequenceAnimalsAntibody SpecificityCation Transport ProteinsCOS CellsDrosophila ProteinsHumansImmunoblottingIn Situ HybridizationKidneyMembrane ProteinsMiceMicrovilliMolecular Sequence DataOrgan SpecificityProtein IsoformsRatsRNA, MessengerSequence AlignmentSequence Analysis, DNASequence Homology, Amino AcidSodium-Hydrogen Exchanger 1Sodium-Hydrogen ExchangersTransfectionConceptsProximal tubulesComplete open reading frameProximal tubule localizationRat renal cortexAmino acid identityOpen reading frameRenal expressionCortical tubulesRenal cortexOuter stripeOuter medullaNull miceMammalian orthologsWestern blotDrosophila melanogasterMouse kidneyMedullaMembrane ion transportProtein expressionAcid identityNHE8CortexMammalian isoformsReading frameNHE isoforms
1995
Ontogeny of rabbit renal cortical NHE3 and NHE1: effect of glucocorticoids
Baum M, Biemesderfer D, Gentry D, Aronson PS. Ontogeny of rabbit renal cortical NHE3 and NHE1: effect of glucocorticoids. American Journal Of Physiology 1995, 268: f815-f820. PMID: 7771509, DOI: 10.1152/ajprenal.1995.268.5.f815.Peer-Reviewed Original ResearchConceptsProximal tubulesNHE1 mRNABicarbonate absorptionNHE3 mRNA abundanceDaily subcutaneous administrationAdult animalsAdministration of glucocorticoidsEffects of glucocorticoidsNHE3 protein abundanceNeonatal proximal tubuleDays of ageRenal maturationSubcutaneous administrationRenal cortexNeonatal rabbitsCortical developmentProtein abundanceRate of maturationGlucocorticoidsNHE3 mRNAAntiporter activityApical membraneNHE3Lower ratesTubules
1992
Immunocytochemical characterization of Na(+)-H+ exchanger isoform NHE-1 in rabbit kidney
Biemesderfer D, Reilly RF, Exner M, Igarashi P, Aronson PS. Immunocytochemical characterization of Na(+)-H+ exchanger isoform NHE-1 in rabbit kidney. American Journal Of Physiology 1992, 263: f833-f840. PMID: 1279986, DOI: 10.1152/ajprenal.1992.263.5.f833.Peer-Reviewed Original ResearchConceptsNHE-1 proteinNHE-1Rabbit kidneyDistal convoluted tubuleMultiple nephron segmentsThick ascending limbWestern blot analysisRenal cortexRabbit renal cortexConvoluted tubulesProximal tubulesAscending limbRabbit nephronTubule cellsGuinea pigsLLC-PK1 cellsNephron segmentsIndirect immunofluorescenceKidneyImmunocytochemical characterizationPrincipal cellsExchanger isoformsBlot analysisFusion proteinAntibodies
1989
Effects of acetazolamide on Na+-HCO-3 cotransport in basolateral membrane vesicles isolated from rabbit renal cortex.
Soleimani M, Aronson PS. Effects of acetazolamide on Na+-HCO-3 cotransport in basolateral membrane vesicles isolated from rabbit renal cortex. Journal Of Clinical Investigation 1989, 83: 945-951. PMID: 2921327, PMCID: PMC303770, DOI: 10.1172/jci113980.Peer-Reviewed Original ResearchMeSH Keywords4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic AcidAcetatesAcetazolamideAmmoniaAnimalsBicarbonatesBiological TransportCarrier ProteinsCell MembraneHydrogen-Ion ConcentrationKidney CortexMaleRabbitsSodiumSodium-Bicarbonate Symporters
1986
Na+/HCO3-co-transport in basolateral membrane vesicles isolated from rabbit renal cortex.
Grassl SM, Aronson PS. Na+/HCO3-co-transport in basolateral membrane vesicles isolated from rabbit renal cortex. Journal Of Biological Chemistry 1986, 261: 8778-8783. PMID: 3013862, DOI: 10.1016/s0021-9258(19)84448-4.Peer-Reviewed Original ResearchChapter 4 Molecular Properties and Physiological Roles of the Renal Na+-H+ Exchanger
Aronson P, Igarashi P. Chapter 4 Molecular Properties and Physiological Roles of the Renal Na+-H+ Exchanger. Current Topics In Membranes 1986, 26: 57-75. DOI: 10.1016/s0070-2161(08)60726-1.Chapters
1985
Paradoxical effects of pyrazinoate and nicotinate on urate transport in dog renal microvillus membranes.
Guggino SE, Aronson PS. Paradoxical effects of pyrazinoate and nicotinate on urate transport in dog renal microvillus membranes. Journal Of Clinical Investigation 1985, 76: 543-547. PMID: 4031062, PMCID: PMC423858, DOI: 10.1172/jci112004.Peer-Reviewed Original ResearchConceptsLow dosesParadoxical effectUrate transportProximal tubular cellsUrate accumulationRenal urate excretionCanine renal cortexUrate retentionInside-alkaline pH gradientUricosuric drugsUrate reabsorptionRenal cortexUrate excretionTubular cellsHigh dosesCotransport pathwayDosesSame transport systemPyrazinoateLuminal membraneUrate uptakeAnion exchange pathwayDrugsMicrovillus membrane vesicles
1984
Absence of Cl-OH exchange and NaCl cotransport in rabbit renal microvillus membrane vesicles
Seifter JL, Knickelbein R, Aronson PS. Absence of Cl-OH exchange and NaCl cotransport in rabbit renal microvillus membrane vesicles. American Journal Of Physiology 1984, 247: f753-f759. PMID: 6093589, DOI: 10.1152/ajprenal.1984.247.5.f753.Peer-Reviewed Original Research
1983
Urate transport via anion exchange in dog renal microvillus membrane vesicles
Kahn AM, Aronson PS. Urate transport via anion exchange in dog renal microvillus membrane vesicles. American Journal Of Physiology 1983, 244: f56-f63. PMID: 6849384, DOI: 10.1152/ajprenal.1983.244.1.f56.Peer-Reviewed Original ResearchConceptsDose-response curveP-aminohippurateUrate transportRenal microvillus membrane vesiclesUptake of PAHDog renal cortexMicrovillus membrane vesiclesAnion reabsorptionRenal cortexProximal tubulesTransport of urateUrateBrush border membrane vesiclesMembrane vesiclesUrate uptakePAH uptakeExternal ClPresent studyBorder membrane vesicles
1982
Glucose and alanine inhibition of phosphate transport in renal microvillus membrane vesicles
Barrett PQ, Aronson PS. Glucose and alanine inhibition of phosphate transport in renal microvillus membrane vesicles. American Journal Of Physiology 1982, 242: f126-f131. PMID: 7065130, DOI: 10.1152/ajprenal.1982.242.2.f126.Peer-Reviewed Original Research
1979
Dissociation of proximal tubular glucose and Na+ reabsorption by amphotericin B
Aronson PS, Hayslett JP, Kashgarian M. Dissociation of proximal tubular glucose and Na+ reabsorption by amphotericin B. American Journal Of Physiology 1979, 236: f392-f397. PMID: 434214, DOI: 10.1152/ajprenal.1979.236.4.f392.Peer-Reviewed Original ResearchConceptsAmphotericin BGlucose reabsorptionProximal tubulesNecturus proximal tubuleGlucose uptakeTubular glucose reabsorptionStopped-flow microperfusionRenal cortexRabbit renal cortexTubular lumenReabsorptionLuminal membraneGlucoseMicrovillus membrane vesiclesTubulesUptakeAmphotericinMembrane vesicle preparationsMicroperfusion