1996
Numerical relationship between neurons in the lateral geniculate nucleus and primary visual cortex in macaque monkeys
Suner I, Rakic P. Numerical relationship between neurons in the lateral geniculate nucleus and primary visual cortex in macaque monkeys. Visual Neuroscience 1996, 13: 585-590. PMID: 8782386, DOI: 10.1017/s0952523800008269.Peer-Reviewed Original ResearchConceptsLateral geniculate nucleusArea 17Primary visual cortexGeniculate nucleusVisual cortexThree-dimensional counting methodTotal neuron numberNormal rhesus monkeysVisual centersCerebral hemispheresMacaque monkeysRhesus monkeysNeuron numberNeuronsNumber of neuronsRight sideCortexTotal populationMonkeysMultiple factorsSame side
1995
Tempo of neurogenesis and synaptogenesis in the primate cingulate mesocortex: Comparison with the neocortex
Granger B, Tekaia F, Le Sourd A, Rakic P, Bourgeois J. Tempo of neurogenesis and synaptogenesis in the primate cingulate mesocortex: Comparison with the neocortex. The Journal Of Comparative Neurology 1995, 360: 363-376. PMID: 8522653, DOI: 10.1002/cne.903600212.Peer-Reviewed Original ResearchConceptsEnd of neurogenesisArea 24Area 17Neocortical areasEmbryonic days (EDs) 70Postnatal rhesus monkeysSecond postnatal monthPrimary visual cortexRemainder of gestationAnterior cingulate cortexSynaptic densityPostnatal monthRapid phaseHumoral factorsCingulate cortexVisual cortexAssociational areasRhesus monkeysNeurogenesisDay 70SynaptogenesisAutoradiographic analysisMonthsMesocortexNeocortex
1993
Changes of synaptic density in the primary visual cortex of the macaque monkey from fetal to adult stage
Bourgeois J, Rakic P. Changes of synaptic density in the primary visual cortex of the macaque monkey from fetal to adult stage. Journal Of Neuroscience 1993, 13: 2801-2820. PMID: 8331373, PMCID: PMC6576672, DOI: 10.1523/jneurosci.13-07-02801.1993.Peer-Reviewed Original ResearchConceptsPrimary visual cortexSynaptic contactsVisual cortexCortical plateSynaptic densityDendritic spinesPostnatal yearDensity of synapsesThird postnatal monthFirst postnatal yearTime of pubertyMicrons 3Asymmetric synapsesDendritic shaftsLayer VICalcarine fissureCortical neuronsLayer IVPostnatal monthLaminar positionMacaque monkeysFunctional maturationRhesus monkeysAdult levelsNeuropil
1991
A novel cytoarchitectonic area induced experimentally within the primate visual cortex.
Rakic P, Suñer I, Williams R. A novel cytoarchitectonic area induced experimentally within the primate visual cortex. Proceedings Of The National Academy Of Sciences Of The United States Of America 1991, 88: 2083-2087. PMID: 2006147, PMCID: PMC51173, DOI: 10.1073/pnas.88.6.2083.Peer-Reviewed Original ResearchConceptsArea 17Cytoarchitectonic areasVisual cortexSecondary visual cortexPrimary visual cortexPrimate visual cortexAfferent fibersCerebral cortexCortical neuronsThalamic inputsCortical connectionsThalamic fibersCytoarchitectonic regionsCortexCortical parcellationAberrant combinationsArea XProtomap hypothesisCell-cell interactionsNeurons
1989
Synaptogenesis in visual cortex of normal and preterm monkeys: evidence for intrinsic regulation of synaptic overproduction.
Bourgeois J, Jastreboff P, Rakic P. Synaptogenesis in visual cortex of normal and preterm monkeys: evidence for intrinsic regulation of synaptic overproduction. Proceedings Of The National Academy Of Sciences Of The United States Of America 1989, 86: 4297-4301. PMID: 2726773, PMCID: PMC287439, DOI: 10.1073/pnas.86.11.4297.Peer-Reviewed Original ResearchConceptsVisual cortexSynaptic overproductionVisual stimulationFirst postnatal monthTime of deliveryAge-matched controlsPrimary visual cortexTime of conceptionControl infantsLaminar distributionPostnatal monthRhesus monkeysCortexQuantitative electron microscopyVisual experienceTime courseSynapsesStimulationMonkeysIntrinsic regulationOverproductionPretermInfantsFetusesWeeksQuantitative autoradiographic mapping of serotonin 5‐HT1 and 5‐HT2 receptors and uptake sites in the neocortex of the rhesus monkey
Lidow M, Goldman‐Rakic P, Gallager D, Rakic P. Quantitative autoradiographic mapping of serotonin 5‐HT1 and 5‐HT2 receptors and uptake sites in the neocortex of the rhesus monkey. The Journal Of Comparative Neurology 1989, 280: 27-42. PMID: 2918094, DOI: 10.1002/cne.902800104.Peer-Reviewed Original ResearchConceptsLayer IIIReceptor subtypesUptake sitesCortical areasVisual cortexLayer IRhesus monkeysPrimary motor cortexSerotonin uptake sitesQuantitative autoradiographic mappingMonkey cerebral cortexDistribution of serotoninPrimary visual cortexPattern of distributionIVC betaAutoradiographic mappingCerebral cortexMotor cortexLayer IVCortical functionOccipital lobePrimary motorPrestriate cortexReceptor distributionCortexNeuropeptide Y-Containing Neurons are Situated Predominantly Outside Cytochrome Oxidase Puffs in Macaque Visual Cortex
Kuljis R, Rakic P. Neuropeptide Y-Containing Neurons are Situated Predominantly Outside Cytochrome Oxidase Puffs in Macaque Visual Cortex. Visual Neuroscience 1989, 2: 57-62. PMID: 2562144, DOI: 10.1017/s0952523800004326.Peer-Reviewed Original ResearchConceptsNeuropeptide YVisual cortexLayers II/IIINumber of NPYLocal circuit neuronsCortico-cortical connectivityCytochrome oxidase histochemistryPrimary visual cortexReceptive field propertiesMacaque visual cortexCircuit neuronsInhibitory GABASynaptic terminalsInterpuffsImmunocytochemical methodsNeuronsEqual volumeCortexPuffsGABA
1988
Differential quenching and limits of resolution in autoradiograms of brain tissue labeled with3H-,125I- and14C-compounds
Lidow M, Goldman-Rakic P, Rakic P, Gallager D. Differential quenching and limits of resolution in autoradiograms of brain tissue labeled with3H-,125I- and14C-compounds. Brain Research 1988, 459: 105-119. PMID: 3167570, DOI: 10.1016/0006-8993(88)90290-9.Peer-Reviewed Original ResearchConceptsBrain sectionsAdult monkeysBrain tissuePrimary motor cortexPrimary visual cortexAutoradiograms of sectionsAdult rhesus monkeysMotor cortexCortical sectionsLaminar patternLayer IIIPrimate brainVisual cortexRhesus monkeysBrain structuresNeocortexCortexSignificant attenuationAutoradiographic measurementFilm autoradiographyMonkeysAutoradiograms
1984
Region‐specific distribution of catecholamine afferents in primate cerebral cortex: A fluorescence histochemical analysis
Levitt P, Rakic P, Goldman‐Rakic P. Region‐specific distribution of catecholamine afferents in primate cerebral cortex: A fluorescence histochemical analysis. The Journal Of Comparative Neurology 1984, 227: 23-36. PMID: 6470208, DOI: 10.1002/cne.902270105.Peer-Reviewed Original ResearchConceptsCA innervationCerebral cortexCerebral lobesFluorescent axonsRhesus monkeysFirst anatomical demonstrationFluorescence histochemical analysisPrimate cerebral cortexSubjacent white matterPrimary visual cortexConcentration of DAAdult rhesus monkeysDifferent cortical regionsRegion-specific distributionLaminar distributionGyrencephalic brainLayer VICatecholamine afferentsSomatosensory areaFluorescence histochemistryPremotor areasCytoarchitectonic regionsIntracerebral distributionPreterminal axonsLayers II
1983
Geniculo-Cortical Connections in Primates: Normal and Experimentally Altered Development
Rakic P. Geniculo-Cortical Connections in Primates: Normal and Experimentally Altered Development. Progress In Brain Research 1983, 58: 393-404. PMID: 6195694, DOI: 10.1016/s0079-6123(08)60042-4.Peer-Reviewed Original ResearchConceptsVisual cortexDorsal lateral geniculate nucleusFetal rhesus monkeysLateral geniculate nucleusCentral visual pathwaysPrimary visual cortexPrimate visual cortexSynaptic reorganizationCerebral cortexPrenatal mechanismsGeniculate nucleusAfferent connectionsAdult monkeysVisual pathwayRhesus monkeysAnatomical organizationExperimental modelCortexCongenital disorderNormal patternPathological developmentMonkeysColor visionSeries of studiesPrimates
1977
Prenatal development of the visual system in rhesus monkey
Rakic P, Barlow H, Gaze R. Prenatal development of the visual system in rhesus monkey. Philosophical Transactions Of The Royal Society B Biological Sciences 1977, 278: 245-260. PMID: 19781, DOI: 10.1098/rstb.1977.0040.Peer-Reviewed Original ResearchConceptsLateral geniculate bodyRetinal ganglion cellsSuperior colliculusOcular dominance columnsLayer IVFirst retinal ganglion cellsRhesus monkeysDorsal lateral geniculate bodySegregation of afferentsPrenatal developmentAnterograde axoplasmic transportEarly postnatal daysProduction of neuronsPrimary visual cortexJuvenile rhesus monkeysSC projectionsEye injectionTransneuronal transportGeniculate bodyCortical plateGanglion cellsGeniculocortical axonsOptic radiationPostnatal dayOcular dominance