2022
Plasma and Platelet Transfusion Strategies in Critically Ill Children With Malignancy, Acute Liver Failure and/or Liver Transplantation, or Sepsis: From the Transfusion and Anemia EXpertise Initiative–Control/Avoidance of Bleeding
Lieberman L, Karam O, Stanworth SJ, Goobie SM, Crighton G, Goel R, Lacroix J, Nellis ME, Parker RI, Steffen K, Stricker P, Valentine SL, Steiner ME, Network A. Plasma and Platelet Transfusion Strategies in Critically Ill Children With Malignancy, Acute Liver Failure and/or Liver Transplantation, or Sepsis: From the Transfusion and Anemia EXpertise Initiative–Control/Avoidance of Bleeding. Pediatric Critical Care Medicine 2022, 23: e37-e49. PMID: 34989704, PMCID: PMC8769367, DOI: 10.1097/pcc.0000000000002857.Peer-Reviewed Original ResearchConceptsAnemia EXpertise Initiative-Control/AvoidanceAcute liver diseaseLiver transplantationExpert consensus statementLiver diseaseIntravascular coagulationIll neonatesPlatelet transfusionsIll childrenConsensus statementSystematic reviewLos Angeles Appropriateness MethodExpert-based statementsAcute liver failurePlatelet transfusion strategyDevelopment/UniversityCochrane Library databasesBleeding expertsRecommendations AssessmentTransfusion strategyLiver failureTransfusion managementAppropriateness MethodTransfusionSepsis
2021
Performance of Platelet Mass Index as a Marker of Severity for Sepsis and Septic Shock in Children
Chegondi M, Vijayakumar N, Billa R, Badheka A, Karam O. Performance of Platelet Mass Index as a Marker of Severity for Sepsis and Septic Shock in Children. Journal Of Pediatric Intensive Care 2021, 12: 228-234. PMID: 37565022, PMCID: PMC10411082, DOI: 10.1055/s-0041-1731434.Peer-Reviewed Original ResearchPlatelet mass indexPediatric intensive care unitSeptic shockPICU admissionMass indexPrognostic indicatorFl/Day 1Marker of severityRetrospective observational studyIntensive care unitCare unitPediatric sepsisObservational studyClinical valueDay 3SepsisCharacteristic curveFurther studiesAdmissionPMI valuesChildrenAUCSpecificityNonsurvivors
2017
Rapid detection and ruling out of neonatal sepsis by PCR coupled with Electrospray Ionization Mass Spectrometry (PCR/ESI-MS)
Delcò C, Karam O, Pfister R, Gervaix A, Renzi G, Emonet S, Schrenzel J, Posfay-Barbe KM. Rapid detection and ruling out of neonatal sepsis by PCR coupled with Electrospray Ionization Mass Spectrometry (PCR/ESI-MS). Early Human Development 2017, 108: 17-22. PMID: 28343091, DOI: 10.1016/j.earlhumdev.2017.03.004.Peer-Reviewed Original ResearchConceptsNegative predictive valuePCR/ESI-MSBlood culturesPredictive valueNeonatal sepsisGood negative predictive valueProspective observational studyBlood culture resultsInitiation of antibioticsPositive blood culturesConventional blood culturePositive predictive valueEmpiric antibioticsConsecutive neonatesAdverse eventsClinical suspicionMedian ageNeonatal populationObservational studySepsisBlood samplesEarly reassessmentImportant causeCulture resultsBacterial infections
2012
Mortality associated with restrictive threshold for red blood cell transfusion in pediatric patients with sepsis
Karam O, Tucci M, Ducruet T, Hume H, Lacroix J, Gauvin F. Mortality associated with restrictive threshold for red blood cell transfusion in pediatric patients with sepsis. Pediatric Critical Care Medicine 2012, 13: 495. DOI: 10.1097/pcc.0b013e31824fbefe.Peer-Reviewed Original Research