2024
Comprehensive secondary analysis of thrombotic events in pediatric patients receiving extracorporeal membrane oxygenation: A prospective cohort study.
Hughes T, Treffalls R, Koek W, Dalton H, Karam O, Meyer A. Comprehensive secondary analysis of thrombotic events in pediatric patients receiving extracorporeal membrane oxygenation: A prospective cohort study. Perfusion 2024, 2676591241289358. PMID: 39352407, DOI: 10.1177/02676591241289358.Peer-Reviewed Original ResearchExtracorporeal membrane oxygenationMultiple thrombotic eventsThrombotic eventsMembrane oxygenationPediatric extracorporeal membrane oxygenationMulti-center prospective studyEvaluate predictive factorsDays of therapyPlatelet transfusion volumeProspective cohort studyTransfusion volumeBinomial regressionPediatric patientsProlonged ECMOPlatelet volumePredictive factorsProspective studyUnivariate analysisAnti-XaCohort studySeverity scoreHigh riskPatientsAntithrombin IIIScoring tool
2021
Epidemiology of the Use of Hemostatic Agents in Children Supported by Extracorporeal Membrane Oxygenation: A Pediatric Health Information System Database Study
Nellis ME, Vasovic LV, Goel R, Karam O. Epidemiology of the Use of Hemostatic Agents in Children Supported by Extracorporeal Membrane Oxygenation: A Pediatric Health Information System Database Study. Frontiers In Pediatrics 2021, 9: 673613. PMID: 34041211, PMCID: PMC8141845, DOI: 10.3389/fped.2021.673613.Peer-Reviewed Original ResearchHemostatic blood productsECMO daysPercent of childrenBlood productsMembrane oxygenationPediatric Health Information System Database StudyPediatric Health Information System databaseHealth Information System databaseUse of TXAHospital mortality rateRetrospective observational studyU.S. children's hospitalsExtracorporeal membrane oxygenationMedian ageChildren's HospitalMedian lengthHemostatic measuresInformation System databaseObservational studyECMODatabase studyHigh riskMortality rateHemostatic agentsFactor VIIa
2020
Individual‐ and hospital‐level correlates of red blood cell, platelet, and plasma transfusions among hospitalized children and neonates: a nationally representative study in the United States
Goel R, Josephson CD, Patel EU, Petersen MR, Packman Z, Gehrie E, Bloch EM, Lokhandwala P, Ness PM, Katz L, Nellis M, Karam O, Tobian AAR. Individual‐ and hospital‐level correlates of red blood cell, platelet, and plasma transfusions among hospitalized children and neonates: a nationally representative study in the United States. Transfusion 2020, 60: 1700-1712. PMID: 32589286, PMCID: PMC7951993, DOI: 10.1111/trf.15855.Peer-Reviewed Original ResearchConceptsAdjusted odds ratioRed blood cellsRBC transfusionPlatelet transfusionsPlasma transfusionAge groupsBlood cellsElective admission statusProportion of neonatesMultivariable logistic regressionOlder age groupsTotal hospitalizationsPrimary outcomeSecondary outcomesHospitalized neonatesNonwhite raceHospitalized childrenFemale sexOverall prevalenceOdds ratioHospital birthsPediatric dischargesTransfusion proceduresTransfusionHigh risk