2018
Trends in Outcomes After Cytoreductive Surgery with Hyperthermic Intraperitoneal Chemotherapy
Gani F, Conca-Cheng AM, Nettles B, Ahuja N, Johnston FM. Trends in Outcomes After Cytoreductive Surgery with Hyperthermic Intraperitoneal Chemotherapy. Journal Of Surgical Research 2018, 234: 240-248. PMID: 30527480, DOI: 10.1016/j.jss.2018.09.032.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAged, 80 and overCarcinomaChemotherapy, Cancer, Regional PerfusionCombined Modality TherapyCytoreduction Surgical ProceduresDatabases, FactualFemaleHumansHyperthermia, InducedLogistic ModelsMaleMiddle AgedPatient SelectionPeritoneal NeoplasmsPostoperative ComplicationsRisk FactorsTreatment OutcomeConceptsCRS/HIPECHyperthermic intraperitoneal chemotherapyMedian operative timeLength of stayPostoperative morbidityCytoreductive surgeryOperative timeIntraperitoneal chemotherapySelect patientsClinical outcomesSurgeons National Surgical Quality Improvement Program databaseNational Surgical Quality Improvement Program databaseCommon primary tumor siteQuality Improvement Program databaseMultivariable logistic regression analysisLow preoperative hematocritImprovement Program databasePreoperative serum albuminCareful patient selectionPrimary tumor siteLogistic regression analysisPostoperative complicationsPostoperative deathsPreoperative hematocritPeritoneal carcinomatosis
2013
KRAS G>A mutation favors poor tumor differentiation but may not be associated with prognosis in patients with curatively resected duodenal adenocarcinoma
Fu T, Guzzetta AA, Jeschke J, Vatapalli R, Dave P, Hooker CM, Morgan R, Iacobuzio‐Donahue C, Liu B, Ahuja N. KRAS G>A mutation favors poor tumor differentiation but may not be associated with prognosis in patients with curatively resected duodenal adenocarcinoma. International Journal Of Cancer 2013, 132: 2502-2509. PMID: 23065691, PMCID: PMC3579006, DOI: 10.1002/ijc.27910.Peer-Reviewed Original ResearchMeSH KeywordsAdenocarcinomaBiomarkers, TumorCell DifferentiationDNA, NeoplasmDuodenal NeoplasmsFemaleHumansMaleMicrosatellite RepeatsMiddle AgedMutationNeoplasm Recurrence, LocalNeoplasm StagingPolymerase Chain ReactionPrognosisProto-Oncogene ProteinsProto-Oncogene Proteins p21(ras)Ras ProteinsSurvival RateConceptsPoor tumor differentiationKRAS GPositive lymph nodesDuodenal adenocarcinomaKRAS mutationsTumor differentiationMutation carriersDistant relapseLymph nodesMultivariate logistic regression analysisShorter relapse-free survivalFuture staging systemsRelapse-free survivalShorter overall survivalPossible prognostic roleLogistic regression analysisCurative resectionPoor OSOverall survivalPrognostic roleTumor characteristicsClinical outcomesClinicopathological characteristicsPoor prognosisPrognostic significance
2010
Asian Race/Ethnicity as a Risk Factor for Bile Duct Injury During Cholecystectomy
Downing SR, Datoo G, Oyetunji TA, Fullum T, Chang DC, Ahuja N. Asian Race/Ethnicity as a Risk Factor for Bile Duct Injury During Cholecystectomy. JAMA Surgery 2010, 145: 785-787. PMID: 20713933, PMCID: PMC4086633, DOI: 10.1001/archsurg.2010.131.Peer-Reviewed Original ResearchConceptsBile duct injuryAsian race/ethnicityRace/ethnicitySignificant risk factorsRisk factorsDuct injuryIatrogenic bile duct injuryMultivariate logistic regression analysisAberrant biliary anatomyHospital days 0Nationwide Inpatient SampleLogistic regression analysisAcute cholecystitisOpen cholecystectomySerious complicationsMale sexBiliary anatomyInpatient SampleCholecystectomyDay 0Older ageLaparoscopicRegression analysisInjuryProcedure codes