Clinicopathologic Presentation and Natural History of Anorectal Melanoma: A Case Series of 18 Patients
Hicks CW, Pappou EP, Magruder JT, Gazer B, Fang S, Wick EC, Gearhart SL, Ahuja N, Efron JE. Clinicopathologic Presentation and Natural History of Anorectal Melanoma: A Case Series of 18 Patients. JAMA Surgery 2014, 149: 608-611. PMID: 24848283, DOI: 10.1001/jamasurg.2013.4643.Peer-Reviewed Original ResearchConceptsAnorectal melanomaOverall disease-specific mortalityNatural historyDisease-specific mortalityDisease-specific survivalNonspecific presenting symptomsWide local excisionRare malignant neoplasmVariable natural historyNonspecific presentationPresenting symptomAbdominoperineal resectionLocal excisionCase seriesMedian timeSurgical managementRectal lesionsMalignant neoplasmsPrognostic parametersClinicopathologic presentationLate diagnosisAdvanced stageIncorrect diagnosisSmall lesionsLarger study