2017
A translational approach for NMDA receptor profiling as a vulnerability biomarker for depression and schizophrenia
Gunduz‐Bruce H, Kenney J, Changlani S, Peixoto A, Gueorguieva R, Leone C, Stachenfeld N. A translational approach for NMDA receptor profiling as a vulnerability biomarker for depression and schizophrenia. Quarterly Journal Of Experimental Physiology And Cognate Medical Sciences 2017, 102: 587-597. PMID: 28294453, DOI: 10.1113/ep086212.Peer-Reviewed Original ResearchConceptsSubgroup of patientsHealthy control subjectsNMDA receptorsControl subjectsDepressed patientsAVP releaseAnimal studiesSchizophrenic subjectsTranslational approachVivo evidenceRecent clinical trialsNMDA receptor functionPlasma arginine vasopressin concentrationNMDA receptor activityHypertonic saline infusionNMDA antagonist ketamineArginine vasopressin concentrationHypertonic salineInverse associationClinical trialsHealthy controlsSaline infusionGlutamate signalingSchizophrenic patientsVasopressin concentration
1994
Effect of athletic training on heart rate variability
Sacknoff D, Gleim G, Stachenfeld N, Coplan N. Effect of athletic training on heart rate variability. American Heart Journal 1994, 127: 1275-1278. PMID: 8172056, DOI: 10.1016/0002-8703(94)90046-9.Peer-Reviewed Original ResearchConceptsHeart rate variabilityRate variabilityParasympathetic toneControl subjectsHeart diseaseVagal activityBaseline parasympathetic toneCardiac vagal toneFrequency domain variablesChronic exerciseHabitual exercisePrognostic stratificationVagal toneControl groupEndurance athletesActivity levelsPatientsAthletic trainingAthletesDiseaseToneExerciseAccurate indicatorSubjectsPrognosis