2006
Synchrony of High Endothelial Venules and Lymphatic Vessels Revealed by Immunization
Liao S, Ruddle NH. Synchrony of High Endothelial Venules and Lymphatic Vessels Revealed by Immunization. The Journal Of Immunology 2006, 177: 3369-3379. PMID: 16920978, DOI: 10.4049/jimmunol.177.5.3369.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsBiomarkersB-LymphocytesCell Adhesion MoleculesCell CommunicationCells, CulturedDendritic CellsDown-RegulationEndotheliumImmunizationLymphangiogenesisLymphatic VesselsLymphotoxin beta ReceptorMiceMice, Inbred C57BLMice, KnockoutMucoproteinsOxazolonePhenotypeReceptors, Tumor Necrosis FactorTime FactorsT-LymphocytesVenulesConceptsHigh endothelial venulesB cellsEndothelial venulesPLN high endothelial venulesPeripheral lymph node high endothelial venulesLymph node high endothelial venulesMature phenotypeLTbetaR-Ig treatmentT cell primingLYVE-1Evans blue dyeLymphotoxin beta receptorLTbetaR-IgCell primingLV functionOVA immunizationImmature phenotypeDay 7Day 4Functional insufficiencyImmunizationClose physical contactLVRemodeling processLymphatic vessels
1993
T Helper 1 (TH1) Functional Phenotype of Human Myelin Basic Protein-Specific T Lymphocytes
Voskuhl R, Martin R, Bergman C, Dalal M, Ruddle N, Mcfarland H. T Helper 1 (TH1) Functional Phenotype of Human Myelin Basic Protein-Specific T Lymphocytes. Autoimmunity 1993, 15: 137-143. PMID: 7692995, DOI: 10.3109/08916939309043888.Peer-Reviewed Original ResearchConceptsExperimental allergic encephalomyelitisMyelin basic proteinMultiple sclerosisT cell linesT cellsMyelin basic protein-specific T lymphocytesMBP-specific T cell linesMurine experimental allergic encephalomyelitisMBP-specific T cellsAntigen-specific cytotoxic activityFunctional phenotypeEncephalitogenic T cellsHuman T cell lineCell linesTh1 subtypeCandidate autoantigenAllergic encephalomyelitisAutoimmune diseasesInflammatory cellsTumor necrosisT lymphocytesInterleukin-4Animal modelsImmunodominant regionCurrent report