1999
Murine neurofibroma reversion by antisense RNA for HTLV-I tax
Li C, Horowitz M, Ruddle N. Murine neurofibroma reversion by antisense RNA for HTLV-I tax. Science China Life Sciences 1999, 42: 8-16. PMID: 18726492, DOI: 10.1007/bf02881742.Peer-Reviewed Original ResearchAntisense RNATax proteinCellular genesEndogenous cellular genesReversed transcriptional orientationNeurofibroma cellsCell morphologyNeurofibroma cell linesTranscriptional orientationHTLV-I Tax proteinProto-oncogene expressionActin mRNAC-MycRetrovirus vectorGenesProteinRNACell linesTax geneMRNAM-CSFTax cDNAExpressionGrowth characteristicsPhenotype
1987
Lymphotoxin: Cloning, Regulation and Mechanism of Killing
Ruddle N, Li C, Tang W, Gray P, McGrath K. Lymphotoxin: Cloning, Regulation and Mechanism of Killing. Novartis Foundation Symposia 1987, 131: 64-87. PMID: 3502460, DOI: 10.1002/9780470513521.ch6.Peer-Reviewed Original ResearchConceptsCDNA libraryBamHI fragmentMurine genomic libraryFull-length cDNACOS-1 cellsCell linesT cell linesNorthern blot analysisGenomic libraryMechanism of killingCDNA probeDNA fragmentationChromosome 17T cell receptorRNABlot analysisCDNAGenesCell receptorCell clonesCellsTarget cellsFragmentsMRNA expressionCloning