1997
Mediators of inflammation
Sacca R, Cuff C, Ruddle N. Mediators of inflammation. Current Opinion In Immunology 1997, 9: 851-857. PMID: 9492989, DOI: 10.1016/s0952-7915(97)80189-6.Peer-Reviewed Original Research
1985
A comparison of lysis mediated by Lyt 2+ TNP-specific cytotoxic-T-lymphocyte (CTL) lines with that mediated by rapidly internalized lymphotoxin-containing supernatant fluids: Evidence for a role of soluble mediators in CTL-mediated killing
Schmid D, Powell M, Mahoney K, Ruddle N. A comparison of lysis mediated by Lyt 2+ TNP-specific cytotoxic-T-lymphocyte (CTL) lines with that mediated by rapidly internalized lymphotoxin-containing supernatant fluids: Evidence for a role of soluble mediators in CTL-mediated killing. Cellular Immunology 1985, 93: 68-82. PMID: 3873290, DOI: 10.1016/0008-8749(85)90389-2.Peer-Reviewed Original ResearchConceptsLyt-2Soluble mediatorsT cell-mediated lysisCytotoxic T lymphocyte lineSpecific T cell linesTarget cellsCytotoxic T lymphocytesDose-dependent fashionSupernatant fluidT cell linesSyngeneic splenocytesAppropriate target cellsT lymphocytesCytoplasm of fibroblastsLymphotoxinMild hypotonic shockLytic processLethal hitPreliminary evidenceMediatorsHypotonic shockLethal effectsCellsFibroblastsOsmotic procedure