2008
Milrinone Use Is Associated With Postoperative Atrial Fibrillation After Cardiac Surgery
Fleming GA, Murray KT, Yu C, Byrne JG, Greelish JP, Petracek MR, Hoff SJ, Ball SK, Brown NJ, Pretorius M. Milrinone Use Is Associated With Postoperative Atrial Fibrillation After Cardiac Surgery. Circulation 2008, 118: 1619-1625. PMID: 18824641, PMCID: PMC2770257, DOI: 10.1161/circulationaha.108.790162.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAtrial FibrillationCardiac Surgical ProceduresCardiotonic AgentsCoronary DiseaseElective Surgical ProceduresFemaleHumansHypertensionLength of StayLogistic ModelsMaleMiddle AgedMilrinoneMitral Valve InsufficiencyMultivariate AnalysisPostoperative ComplicationsPulmonary Wedge PressureRisk FactorsConceptsPostoperative atrial fibrillationPulmonary artery pressureElective cardiac surgeryMilrinone useMitral valve surgeryAtrial fibrillationCardiac surgeryArtery pressureValve surgeryInotropic drugsEjection fractionRisk factorsLow preoperative ejection fractionHigh pulmonary artery pressurePerioperative risk factorsPreoperative ejection fractionRight ventricular dysfunctionIndependent risk factorPulmonary artery catheterMultivariable logistic regressionProlong hospitalizationVentricular dysfunctionArtery catheterFrequent complicationVentricular function
2002
Potential Roles of Plasminogen Activator System in Coronary Vascular Remodeling Induced by Long-term Nitric Oxide Synthase Inhibition
Kaikita K, Schoenhard JA, Painter CA, Ripley RT, Brown NJ, Fogo AB, Vaughan DE. Potential Roles of Plasminogen Activator System in Coronary Vascular Remodeling Induced by Long-term Nitric Oxide Synthase Inhibition. Journal Of Molecular And Cellular Cardiology 2002, 34: 617-627. PMID: 12054849, DOI: 10.1006/jmcc.2002.2001.Peer-Reviewed Original ResearchConceptsSystolic blood pressureNitric oxide synthase inhibitionOxide synthase inhibitionPerivascular fibrosisBlood pressurePAI-1 deficiencyCoronary perivascular fibrosisPlasminogen activator systemL-NAMENOS inhibitionSynthase inhibitionDeficient miceVascular pathologyLong-term nitric oxide synthase inhibitionNitro-L-arginine methyl esterL-NAME-induced hypertensionLong-term NOS inhibitionPlasma TGF-beta1 levelsPlasminogen activator inhibitor-1-deficient miceStructural vascular changesTGF-beta1 levelsLong-term treatmentTissue-type plasminogen activator-deficient miceWeek study periodActivator system