Metabolism of bradykinin In vivo in humans: identification of BK1-5 as a stable plasma peptide metabolite.
Murphey LJ, Hachey DL, Oates JA, Morrow JD, Brown NJ. Metabolism of bradykinin In vivo in humans: identification of BK1-5 as a stable plasma peptide metabolite. Journal Of Pharmacology And Experimental Therapeutics 2000, 294: 263-9. PMID: 10871321.Peer-Reviewed Original ResearchConceptsBK1-5Stable metaboliteRole of bradykininMetabolism of bradykininDose of bradykininInfused bradykininBradykinin infusionVenous plasmaExogenous bradykininPlasma concentrationsPharmacologic alterationsSystemic circulationFmol/Total doseBradykinin generationPlasma metabolitesHuman volunteersBradykininDisease statesInfusionBloodDoseMetabolitesAmino acid fragmentHuman diseases