2019
Higher urinary cortisol levels associate with increased cardiovascular risk
Haas AV, Hopkins PN, Brown NJ, Pojoga LH, Williams JS, Adler GK, Williams GH. Higher urinary cortisol levels associate with increased cardiovascular risk. Endocrine Connections 2019, 8: 634-640. PMID: 31018177, PMCID: PMC6528405, DOI: 10.1530/ec-19-0182.Peer-Reviewed Original ResearchFramingham risk scoreCardiovascular riskRisk allele carriersRisk scoreAllele carriersCortisol groupCortisol levelsHigher urinary cortisol levelsUrine free cortisolNon-risk allele carriersNon-diabetic individualsBlood pressure measurementsCross-sectional studyRisk allele statusUrinary cortisol levelsIndependent predictorsUrinary cortisolBlood samplesDiscordant findingsLarger sample sizeMultivariate analysisAllele statusCortisol collectionRisk allelesSample size
2007
Plasminogen Activator Inhibitor-1 as a Predictor of Postoperative Atrial Fibrillation After Cardiopulmonary Bypass
Pretorius M, Donahue BS, Yu C, Greelish JP, Roden DM, Brown NJ. Plasminogen Activator Inhibitor-1 as a Predictor of Postoperative Atrial Fibrillation After Cardiopulmonary Bypass. Circulation 2007, 116: i-1-i-7. PMID: 17846288, DOI: 10.1161/circulationaha.106.677906.Peer-Reviewed Original ResearchConceptsPostoperative atrial fibrillationPAI-1 antigen concentrationsCardiopulmonary bypassAtrial fibrillationPlasminogen activator inhibitor-1Remote historyIndependent predictorsActivator inhibitor-1Antigen concentrationPAI-1Development of AFRisk of AFInhibitor-1Administration of protaminePreoperative PAI-1Elective cardiac surgeryTime of surgeryPAI-1 concentrationsBlood of patientsHospital stayValve surgeryAdult patientsYounger patientsCardiac surgerySignificant morbidity