2020
A Chelate-Free Nano-Platform for Incorporation of Diagnostic and Therapeutic Isotopes
Gholami Y, Josephson L, Akam E, Caravan P, Wilks M, Pan X, Maschmeyer R, Kolnick A, Fakhri G, Normandin M, Kuncic Z, Yuan H. A Chelate-Free Nano-Platform for Incorporation of Diagnostic and Therapeutic Isotopes. International Journal Of Nanomedicine 2020, 15: 31-47. PMID: 32021163, PMCID: PMC6954846, DOI: 10.2147/ijn.s227931.Peer-Reviewed Original ResearchConceptsDynamic light scatteringRadiochemical yieldSize exclusion chromatographyThin-layer chromatographyEmpty d orbitalsF-orbital electronsD-orbitalsICP-MSRelaxation spectrometryRadioactive isotopologuesMass spectrometryInductively coupled plasma mass spectrometryChelate-freeNonradioactive metalsPositive chargePlasma mass spectrometryFh NPsNanoparticlesReaction timeLight scatteringMetalExclusion chromatographySpectrometryApproved drugsReaction
2018
Development and Application of FASA, a Model for Quantifying Fatty Acid Metabolism Using Stable Isotope Labeling
Argus J, Wilks M, Zhou Q, Hsieh W, Khialeeva E, Hoi X, Bui V, Xu S, Yu A, Wang E, Herschman H, Williams K, Bensinger S. Development and Application of FASA, a Model for Quantifying Fatty Acid Metabolism Using Stable Isotope Labeling. Cell Reports 2018, 25: 2919-2934.e8. PMID: 30517876, PMCID: PMC6432944, DOI: 10.1016/j.celrep.2018.11.041.Peer-Reviewed Original ResearchConceptsFatty acid metabolismHomeostasis of fatty acidsCellular fatty acid contentCellular fatty acid metabolismAcid metabolismMovement of fatty acidsPolyunsaturated fatty acid poolStable isotope labelingFatty acidsFatty acid homeostasisElongation pathwayFatty acid poolAcid homeostasisMetabolic stepsContribution of synthesisAcid poolPro-inflammatory stimuliFatty acid contentIsotope labelingInflammatory signalingAcid contentMetabolismCellsElongationAcid