Histone Demethylase RBP2 Is Critical for Breast Cancer Progression and Metastasis
Cao J, Liu Z, Cheung WK, Zhao M, Chen SY, Chan SW, Booth CJ, Nguyen DX, Yan Q. Histone Demethylase RBP2 Is Critical for Breast Cancer Progression and Metastasis. Cell Reports 2014, 6: 868-877. PMID: 24582965, PMCID: PMC4014129, DOI: 10.1016/j.celrep.2014.02.004.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsBreast NeoplasmsCell Line, TumorDisease ProgressionEpigenesis, GeneticFemaleGene Expression Regulation, NeoplasticHistone DemethylasesHumansMaleMammary Neoplasms, ExperimentalMiceMice, Inbred NODMice, SCIDMice, TransgenicNeoplasm MetastasisRetinol-Binding Proteins, CellularTransfectionConceptsHistone demethylase RBP2MMTV-neu transgenic miceHuman breast cancer cellsMajor clinical challengeBreast cancer metastasisBreast cancer progressionBreast cancer cellsClinical challengeBreast cancer gene expression data setsTherapeutic targetingTransgenic miceMetastasisMetastatic progressionPutative mediatorsTumor progressionCancer metastasisCancer treatmentCancer progressionTumor metastasisTumor formationCancer cellsProgressionAberrant epigenetic modificationsMetastasis genesMice