1990
Regulation of protein phosphorylation in ocular ciliary epithelial cells by A, C and Ca2+calmodulin-dependent protein kinases
Lopez-Briones L, Wax M, Coca-Prados M. Regulation of protein phosphorylation in ocular ciliary epithelial cells by A, C and Ca2+calmodulin-dependent protein kinases. Experimental Eye Research 1990, 51: 277-286. PMID: 2119313, DOI: 10.1016/0014-4835(90)90024-o.Peer-Reviewed Original ResearchConceptsProtein kinaseLate phosphorylationCalcium/calmodulin-dependent protein kinaseCalmodulin-dependent protein kinaseOcular ciliary epithelial cellsProtein phosphorylation eventsPMA treatmentDependent protein kinaseTwo-dimensional polyacrylamide gel electrophoresisIdentification of intracellularProtein kinase ATryptic peptide analysisHuman ocular ciliary epitheliumEndogenous phosphoproteinsPhosphorylation eventsProtein substrates
1989
Receptor-mediated phosphoinositide hydrolysis in human ocular ciliary epithelial cells.
Wax M, Coca-Prados M. Receptor-mediated phosphoinositide hydrolysis in human ocular ciliary epithelial cells. Investigative Ophthalmology & Visual Science 1989, 30: 1675-9. PMID: 2545648.Peer-Reviewed Original ResearchConceptsPI hydrolysisReceptor-mediated phosphoinositide hydrolysisEpithelial cellsSelective muscarinic antagonistsInositol phosphatesAccumulation of inositolHydrolysis of phosphoinositidesOcular ciliary epitheliumAFDX-116M3 subtypeMuscarinic antagonistMuscarinic receptorsPutative neurotransmittersEC50 valuesPharmacologic characteristicsCiliary epithelial cellsPeripheral tissuesSpecific antagonistPI breakdownPhosphoinositide hydrolysisArginine vasopressinNonpigmented layerOcular ciliary epithelial cellsCiliary epitheliumMicroCi/