2020
Chapter 68 Lung tissue engineering
Raredon M, Yuan Y, Niklason L. Chapter 68 Lung tissue engineering. 2020, 1273-1285. DOI: 10.1016/b978-0-12-818422-6.00070-8.ChaptersTissue homeostasisTissue-engineered lungsExtracellular matrixHomeostatic levelsPulmonary regenerationCell populationsGas exchangeRegeneration of lungTissue unitsFunctional unitsPrecise mixtureRegenerationTissue engineeringProteinHomeostasisBarrier integrityCellsLung tissue engineeringTissue damageTranslationBroad overview
2019
Engineering of human brain organoids with a functional vascular-like system
Cakir B, Xiang Y, Tanaka Y, Kural MH, Parent M, Kang YJ, Chapeton K, Patterson B, Yuan Y, He CS, Raredon MSB, Dengelegi J, Kim KY, Sun P, Zhong M, Lee S, Patra P, Hyder F, Niklason LE, Lee SH, Yoon YS, Park IH. Engineering of human brain organoids with a functional vascular-like system. Nature Methods 2019, 16: 1169-1175. PMID: 31591580, PMCID: PMC6918722, DOI: 10.1038/s41592-019-0586-5.Peer-Reviewed Original ResearchConceptsHuman cortical organoidsBlood-brain barrier characteristicsTrans-endothelial electrical resistanceVasculature-like structuresHuman brain organoidsHuman brain developmentCortical organoidsFunctional maturationPrenatal brainBrain diseasesBrain developmentHuman embryonic stem cellsBlood vesselsBrain organoidsTight junctionsDiseaseStem cellsOrganoidsVariant 2Nutrient transportersNutrient deliveryCellsEndotheliumMicrovasculature