2010
The contribution of Langerhans cells to cutaneous malignancy
Lewis J, Filler R, Smith DA, Golubets K, Girardi M. The contribution of Langerhans cells to cutaneous malignancy. Trends In Immunology 2010, 31: 460-466. PMID: 21071271, PMCID: PMC3753793, DOI: 10.1016/j.it.2010.10.001.Peer-Reviewed Original ResearchConceptsLangerhans cellsDendritic cellsRole of LCsIntraepidermal dendritic cellsAntigen-presenting cellsDC populationsCutaneous malignanciesImmunological organT cellsAdaptive immunitySkin cancerMalignant transformationEnvironmental exposuresUnique populationPotential roleCancerEpithelial tissuesCellsRecent studiesSkinMigratory changesMalignancyPathogenesisPopulationImmunity
2007
Cutaneous Perspectives on Adaptive Immunity
Girardi M. Cutaneous Perspectives on Adaptive Immunity. Clinical Reviews In Allergy & Immunology 2007, 33: 4-14. PMID: 18094943, DOI: 10.1007/s12016-007-0040-9.Peer-Reviewed Original ResearchConceptsAntigen-specific responsesAdaptive immunityAdaptive immune systemDendritic cellsEffector cellsImmunologic memoryTumor immunosurveillanceInflammatory diseasesT cellsImmune responseImmune systemMajor subsetEndothelial cellsSkinMicrobial defenseImmunocytesImmunityEfficient surveillanceCellsResponseImmunosurveillanceChemokinesCytokinesLymphocytesDamaging agents