2015
Fetal and postnatal ovine mesenteric vascular reactivity
Nair J, Gugino SF, Nielsen LC, Caty MG, Lakshminrusimha S. Fetal and postnatal ovine mesenteric vascular reactivity. Pediatric Research 2015, 79: 575-582. PMID: 26672733, PMCID: PMC4837013, DOI: 10.1038/pr.2015.260.Peer-Reviewed Original ResearchConceptsLate preterm gestationMesenteric arterial reactivityMesenteric vascular reactivityFull-term birthBasal eNOS activityMesenteric vasoconstrictionArterial reactivityEnteral nutritionVasodilator pathwaysPreterm birthVascular reactivityIntestinal circulationMesenteric arteryVasodilatory influencePostnatal lambsRisk factorsENOS activityPDE5 proteinPostnatal periodET-1Ontogenic mechanismsGestationBirthMRNAMA rings
2001
Intestinal and Hemodynamic Impairment Following Mesenteric Ischemia/Reperfusion
Khanna A, Rossman J, Fung H, Caty M. Intestinal and Hemodynamic Impairment Following Mesenteric Ischemia/Reperfusion. Journal Of Surgical Research 2001, 99: 114-119. PMID: 11421612, DOI: 10.1006/jsre.2001.6103.Peer-Reviewed Original ResearchConceptsMean arterial pressureR injuryRat modelHeart rateAnimal modelsMesenteric ischemia/reperfusionBarrier functionReperfusion injury resultsSuperior mesenteric arteryIschemia/reperfusionNormal barrier functionArterial pressureHemodynamic effectsIntestinal damageMesenteric occlusionHemodynamic measurementsMesenteric arterySmall bowelFemoral arterySustained fallIntestinal permeabilityInjury resultsAnesthetized ratsIntestinal impairmentHistological disruption
1997
Oxygenated intraluminal perfluorocarbon protects intestinal muscosa from ischemia/reperfusion injury
O'Donnell K, Caty M, Zheng S, Rossman J, Azizkhan R. Oxygenated intraluminal perfluorocarbon protects intestinal muscosa from ischemia/reperfusion injury. Journal Of Pediatric Surgery 1997, 32: 361-365. PMID: 9044154, DOI: 10.1016/s0022-3468(97)90211-6.Peer-Reviewed Original ResearchConceptsIschemia/reperfusion injurySuperior mesenteric arteryMucosal injuryReperfusion injuryMucosal integrityOxygenated perfluorocarbonNew treatment modalitiesR groupMesenteric insufficiencyR injuryMesenteric arteryMucosal functionTreatment modalitiesIntraluminal perfusionMucosal preservationIschemic disordersRat modelIntraluminal flowIntestinal mucosaClinical situationsInjuryIschemiaTissue sectionsReperfusionFeasible technique