2023
ASAM Clinical Considerations: Buprenorphine Treatment of Opioid Use Disorder for Individuals Using High-potency Synthetic Opioids
Weimer M, Herring A, Kawasaki S, Meyer M, Kleykamp B, Ramsey K. ASAM Clinical Considerations: Buprenorphine Treatment of Opioid Use Disorder for Individuals Using High-potency Synthetic Opioids. Journal Of Addiction Medicine 2023, 17: 632-639. PMID: 37934520, DOI: 10.1097/adm.0000000000001202.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsHigh potency synthetic opioidsOpioid use disorderBuprenorphine initiationBuprenorphine treatmentTreatment needsUse disordersClinical considerationsExpert consensusSynthetic opioidsTreatment of OUDProspective researchOpioid agonist treatmentLong-term treatmentDrug supplyPatients' treatment needsOpioid withdrawalBuprenorphine doseOUD treatmentAgonist treatmentDosing frequencyClinical questionsFrontline cliniciansClinical practiceTreatment settingsIndividualized strategiesBetter care at the bedside for hospitalized patients with opioid use disorder
Calcaterra S, Buresh M, Weimer M. Better care at the bedside for hospitalized patients with opioid use disorder. Journal Of Hospital Medicine 2023, 18: 1134-1138. PMID: 37016586, PMCID: PMC10548352, DOI: 10.1002/jhm.13099.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsLow-dose Initiation of Buprenorphine in Hospitalized Patients Using Buccal Buprenorphine: A Case Series
Adams K, Cohen S, Guerra M, Weimer M. Low-dose Initiation of Buprenorphine in Hospitalized Patients Using Buccal Buprenorphine: A Case Series. Journal Of Addiction Medicine 2023, 17: 474-476. PMID: 37579114, DOI: 10.1097/adm.0000000000001146.Peer-Reviewed Original ResearchConceptsOpioid use disorderBuprenorphine initiationSublingual buprenorphineChronic painBuccal buprenorphineCase seriesClinical Opiate Withdrawal Scale (COWS) scoresAddiction medicine serviceLow dose initiationSevere opioid withdrawalHistory of heroinOutpatient opioidsOpioid withdrawalAcute painFentanyl useHospitalized patientsMedian lengthPrescription refillsMedian numberModerate withdrawalInitiation strategiesBuprenorphineMedicine servicePatientsUse disordersPrecipitated Opioid Withdrawal Treated With Ketamine in a Hospitalized Patient: A Case Report
Christian N, Butner J, Evarts M, Weimer M. Precipitated Opioid Withdrawal Treated With Ketamine in a Hospitalized Patient: A Case Report. Journal Of Addiction Medicine 2023, 17: 488-490. PMID: 37579118, DOI: 10.1097/adm.0000000000001151.Peer-Reviewed Case Reports and Technical NotesConceptsClinical Opiate Withdrawal Scale (COWS) scoresOpioid use disorderKetamine infusionOpioid withdrawalCase reportUse disordersScale scoreSevere opioid use disorderFull opioid agonistsHours of admissionEmergency department settingFirst case reportInpatient hospital settingLife-saving medicationsReceptor-mediated signalingLack of evidenceMale patientsFentanyl useOpioid agonistsEmergency departmentComplete resolutionDepartment settingClinical dilemmaAppropriate treatmentHospital settingPromoting alcohol treatment engagement post-hospitalization with brief intervention, medications and CBT4CBT: protocol for a randomized clinical trial in a diverse patient population
Edelman E, Rojas-Perez O, Nich C, Corvino J, Frankforter T, Gordon D, Jordan A, Paris, Jr M, Weimer M, Yates B, Williams E, Kiluk B. Promoting alcohol treatment engagement post-hospitalization with brief intervention, medications and CBT4CBT: protocol for a randomized clinical trial in a diverse patient population. Addiction Science & Clinical Practice 2023, 18: 55. PMID: 37726823, PMCID: PMC10510167, DOI: 10.1186/s13722-023-00407-9.Peer-Reviewed Original ResearchConceptsPost-hospital dischargeCognitive behavioral therapySelf-reported alcohol useBrief Negotiation InterviewUse disordersAlcohol use outcomesComputer-based trainingDays post-hospital dischargeAlcohol use disorderBehavioral therapyInitiation of medicationHealth care utilizationHealth promotion advocatesTreatment engagementUse outcomesAlcohol useSecondary outcomesHospitalized patientsPrimary outcomeCare utilizationClinical trialsAcademic hospitalExploratory outcomesAUDProcess evaluation
2022
Top Ten Tips Palliative Care Clinicians Should Know About Buprenorphine
Neale KJ, Weimer MB, Davis MP, Jones KF, Kullgren JG, Kale SS, Childers J, Broglio K, Merlin JS, Peck S, Francis SY, Bango J, Jones CA, Sager Z, Ho JJ. Top Ten Tips Palliative Care Clinicians Should Know About Buprenorphine. Journal Of Palliative Medicine 2022, 26: 120-130. PMID: 36067137, DOI: 10.1089/jpm.2022.0399.Commentaries, Editorials and LettersConceptsPalliative carePain managementPartial mu-opioid receptor agonistSerious illnessMu-opioid receptor agonistTop Ten TipsOpioid use disorderLife-limiting illnessPC cliniciansCare cliniciansOpioid misuseBuprenorphine useReceptor agonistNurse practitionersUse disordersPopulation-wide trendsIllnessBuprenorphineCliniciansPatientsAgonistsPharmacistsPhysiciansCareSocial workersManagement of Infective Endocarditis in People Who Inject Drugs: A Scientific Statement From the American Heart Association
Baddour LM, Weimer MB, Wurcel AG, McElhinney DB, Marks LR, Fanucchi LC, Garrigos Z, Pettersson GB, DeSimone DC, Fever E. Management of Infective Endocarditis in People Who Inject Drugs: A Scientific Statement From the American Heart Association. Circulation 2022, 146: e187-e201. PMID: 36043414, DOI: 10.1161/cir.0000000000001090.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsAmerican Heart AssociationInfective endocarditisHeart AssociationScientific statementInjection drug useAspects of careInfective endocarditis casesEnglish-language articlesRemoval of duplicatesEndocarditis teamVariety of specialistsEndocarditis casesCardiovascular surgeryIncreasing incidenceSubsequent boutEndocarditisHigh riskInitial boutDrug useInfectious diseasesAddiction medicineLiterature searchPreventive measuresUnique populationDrugsManagement of opioid use disorder and associated conditions among hospitalized adults: A Consensus Statement from the Society of Hospital Medicine
Calcaterra SL, Martin M, Bottner R, Englander H, Weinstein Z, Weimer MB, Lambert E, Herzig SJ. Management of opioid use disorder and associated conditions among hospitalized adults: A Consensus Statement from the Society of Hospital Medicine. Journal Of Hospital Medicine 2022, 17: 744-756. PMID: 35880813, PMCID: PMC9474708, DOI: 10.1002/jhm.12893.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsOpioid use disorderConsensus statementHospitalized adultsOpioid withdrawalUse disordersTreatment of OUDDraft statementManagement of OUDHospital medicineAcute pain managementNumber of hospitalizationsHospital-based cliniciansFinal consensus statementOpioid-related overdoseHospital dischargeOpioid usePain managementWorking GroupCare transitionsInpatient settingObservational studyExpert consensusGuidance statementsPatientsSystematic reviewManagement of opioid use disorder, opioid withdrawal, and opioid overdose prevention in hospitalized adults: A systematic review of existing guidelines
Calcaterra SL, Bottner R, Martin M, Englander H, Weinstein ZM, Weimer MB, Lambert E, Ronan MV, Huerta S, Zaman T, Ullal M, Peterkin AF, Torres‐Lockhart K, Buresh M, O'Brien MT, Snyder H, Herzig SJ. Management of opioid use disorder, opioid withdrawal, and opioid overdose prevention in hospitalized adults: A systematic review of existing guidelines. Journal Of Hospital Medicine 2022, 17: 679-692. PMID: 35880821, PMCID: PMC9474657, DOI: 10.1002/jhm.12908.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsOpioid overdose preventionOpioid withdrawalOpioid useOUD treatmentOverdose preventionShort-acting opioid analgesicsOpioid use disorder managementAcute pain managementUse of methadoneOpioid use disorderEvaluation II (AGREE II) instrumentAppraisal of GuidelinesOpioid withdrawal managementUse of multimodalOpioid overdose reversalMethadone initiationNonopioid therapyHospitalized adultsBuprenorphine treatmentOpioid analgesicsPain managementTreatment guidelinesDiagnostic Statistical ManualOvid MEDLINEEdition criteriaThe X Waiver to Prescribe Buprenorphine: The Why and How
Jones K, Ho JJ, Merlin JS, Weimer M, Sager Z, Kapo J, Childers J. The X Waiver to Prescribe Buprenorphine: The Why and How. Journal Of Palliative Medicine 2022, 25: 1021-1023. PMID: 35775892, DOI: 10.1089/jpm.2022.0170.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsClinical Management of Opioid Withdrawal
Torres‐Lockhart K, Lu TY, Weimer MB, Stein MR, Cunningham CO. Clinical Management of Opioid Withdrawal. Addiction 2022, 117: 2540-2550. PMID: 35112746, DOI: 10.1111/add.15818.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsOpioid use disorderOpioid withdrawal managementOpioid withdrawalClinical managementWithdrawal managementLong-term treatmentAppropriate clinical managementPatient-centered approachRelapse prevention strategiesHarm reduction strategiesHigh-risk timeOUD treatmentAppropriate diagnosisOpioid overdoseUse disordersPrevention strategiesTreatment settingsNarrative reviewWithdrawalTreatmentComplex casesManagementRelapsePatientsOverdoseLow‐ and very low‐dose buprenorphine induction: new(ish) uses for an old(ish) medication?
Weimer MB, Fiellin DA. Low‐ and very low‐dose buprenorphine induction: new(ish) uses for an old(ish) medication? Addiction 2022, 117: 1507-1509. PMID: 35032081, DOI: 10.1111/add.15799.Commentaries, Editorials and LettersCardiac surgeons’ perspectives and practices regarding people who use drugs: A scoping review
Muncan B, Kim EK, Amabile A, Weimer MB, Tiako M, Vallabhajosyula P, Kalogeropoulos AP, Geirsson A. Cardiac surgeons’ perspectives and practices regarding people who use drugs: A scoping review. Journal Of Cardiac Surgery 2022, 37: 630-639. PMID: 34989450, DOI: 10.1111/jocs.16201.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsCardiac surgeonsInfective endocarditisAddiction medicine specialistsInfectious disease specialistsMultidisciplinary care teamEvidence-based guidelinesJoanna Briggs Institute guidelinesPoor health outcomesPreferred Reporting ItemsComprehensive literature searchWillingness of surgeonsCardiac complicationsCardiovascular complicationsSurgical treatmentSurgical managementDisease specialistsAim of studyCare teamInstitute guidelinesMedicine specialistsEquitable careIndependent authorsPsychosocial factorsReporting ItemsHealth outcomesCardiac Surgeons’ Practices and Attitudes toward Addiction Care for Patients with Substance use Disorders
Tiako M, Mszar R, Brooks C, Bin Mahmood SU, Mori M, Vallabhajosyula P, Geirsson A, Weimer MB. Cardiac Surgeons’ Practices and Attitudes toward Addiction Care for Patients with Substance use Disorders. Substance Abuse 2022, 43: 206-211. PMID: 34038333, DOI: 10.1080/08897077.2021.1917475.Peer-Reviewed Original ResearchConceptsSubstance use disordersUse disordersCardiac surgeonsSurgeon's practiceAddiction careInjection drug useOpioid use disorderMultivariable logistic regressionCare of patientsQuarter of surgeonsMost hospital settingsMinority of surgeonsMost patientsInfective endocarditisHospital settingAddiction specialistsPatientsMost surgeonsIDUsAddiction servicesLogistic regressionMOUDHealth systemSurgeonsLack of educationAddiction Care Matters: A Practical Guide to Substance Use Disorder Prevention, Screening, and Treatment
Weimer MB. Addiction Care Matters: A Practical Guide to Substance Use Disorder Prevention, Screening, and Treatment. Medical Clinics Of North America 2022, 106: xix-xx. PMID: 34823738, DOI: 10.1016/j.mcna.2021.10.001.Commentaries, Editorials and LettersPerioperative Buprenorphine Management A Multidisciplinary Approach
Hickey T, Abelleira A, Acampora G, Becker WC, Falker CG, Nazario M, Weimer MB. Perioperative Buprenorphine Management A Multidisciplinary Approach. Medical Clinics Of North America 2022, 106: 169-185. PMID: 34823729, DOI: 10.1016/j.mcna.2021.09.001.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsMeSH KeywordsAcetaminophenAgedAnalgesics, Non-NarcoticAnalgesics, OpioidAnti-Inflammatory Agents, Non-SteroidalArthroplasty, Replacement, HipBuprenorphineCombined Modality TherapyDrug CompoundingFemaleHumansInterdisciplinary CommunicationMaleOpiate Substitution TreatmentOpioid-Related DisordersPainPain ManagementPain, PostoperativePerioperative CareReceptors, Opioid, muConceptsOpioid use disorderBuprenorphine treatmentMu-opioid receptor availabilityAgonist opioid treatmentMultimodal analgesic strategyAnti-inflammatory drugsLong-term buprenorphine treatmentAnalgesic strategiesNonopioid adjunctsOpioid treatmentPerioperative strategiesHospital dischargePerioperative managementBuprenorphine formulationsSimultaneous administrationRegional anesthesiaEffective treatmentUse disordersReceptor availabilityMultidisciplinary approachBuprenorphinePatientsTreatmentPainAnesthesiaInfectious Complications of Injection Drug Use
Marks LR, Nolan NS, Liang SY, Durkin MJ, Weimer MB. Infectious Complications of Injection Drug Use. Medical Clinics Of North America 2022, 106: 187-200. PMID: 34823730, DOI: 10.1016/j.mcna.2021.08.006.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsInjection drug useInjection drug use-related infective endocarditisHuman immunodeficiency virusHepatitis C virusInfectious complicationsDrug useCommon infectious complicationOpioid use disorderCommon risk factorsCause of deathOpioid overdose epidemicViral hepatitisInfective endocarditisImmunodeficiency virusClinical syndromeHIV outbreakInfectious disease epidemicsC virusRisk factorsIntravenous administrationOverdose epidemicUse disordersModel of treatmentMedical careInfectious diseases
2021
Low Dose Initiation of Buprenorphine: A Narrative Review and Practical Approach
Cohen SM, Weimer MB, Levander XA, Peckham AM, Tetrault JM, Morford KL. Low Dose Initiation of Buprenorphine: A Narrative Review and Practical Approach. Journal Of Addiction Medicine 2021, 16: 399-406. PMID: 34954746, DOI: 10.1097/adm.0000000000000945.Peer-Reviewed Original ResearchConceptsLow dose initiationFull opioid agonistsDose initiationOpioid withdrawal symptomsOpioid agonistsBuprenorphine doseWithdrawal symptomsHigh potency synthetic opioidsOpioid use disorderAppropriate clinical situationsMu-opioid receptorsBuprenorphine initiationOpioid withdrawalStarting doseOutpatient settingCare coordinationDose changesOverdose deathsCurrent evidenceUse disordersBuprenorphineTherapeutic levelsClinical situationsSynthetic opioidsNarrative reviewThe Need for Multidisciplinary Hospital Teams for Injection Drug Use-related Infective Endocarditis
Weimer MB, Falker CG, Seval N, Golden M, Hull SC, Geirsson A, Vallabhajosyula P. The Need for Multidisciplinary Hospital Teams for Injection Drug Use-related Infective Endocarditis. Journal Of Addiction Medicine 2021, 16: 375-378. PMID: 34510088, DOI: 10.1097/adm.0000000000000916.Commentaries, Editorials and LettersConceptsInjection drug use-related infective endocarditisCardiac surgeryInfective endocarditisAddiction treatmentInjection drug useCare of patientsMultidisciplinary hospital teamSubstance use disordersMost patientsUse disordersPatientsDrug useSurgical needsHospital teamIDUsCase managementInfectious diseasesAddiction medicineMultidisciplinary approachEndocarditisSurgeryTreatmentDiseaseComplex diseasesAnesthesiaX-Waiver Exemption in the Treatment of Opioid Use Disorder—Reply
Weimer MB, Wakeman SE, Saitz R. X-Waiver Exemption in the Treatment of Opioid Use Disorder—Reply. JAMA 2021, 326: 442-443. PMID: 34342621, DOI: 10.1001/jama.2021.8270.Commentaries, Editorials and Letters