2007
Neurokinins robustly activate the majority of septohippocampal cholinergic neurons
Morozova E, Wu M, Dumalska I, Alreja M. Neurokinins robustly activate the majority of septohippocampal cholinergic neurons. European Journal Of Neuroscience 2007, 27: 114-122. PMID: 18184316, DOI: 10.1111/j.1460-9568.2007.05993.x.Peer-Reviewed Original ResearchConceptsSeptohippocampal cholinergic neuronsHippocampal acetylcholine releaseCholinergic neuronsNK3 receptorsHemokinin-1Acetylcholine releaseNK2 receptorsElectrophysiological effectsRat brain slice preparationWhole-cell patch-clamp recordingsMedial septum/diagonal bandDiagonal band neuronsNK3 receptor agonistPost-synaptic mechanismsStress-related affective disordersBrain slice preparationPatch-clamp recordingsEffect of NKCholinergic cellsNK receptorsReceptor agonistSlice preparationDiagonal bandNeurokinin receptorsBrain neurons
2004
Histamine innervation and activation of septohippocampal GABAergic neurones: involvement of local ACh release
Xu C, Michelsen KA, Wu M, Morozova E, Panula P, Alreja M. Histamine innervation and activation of septohippocampal GABAergic neurones: involvement of local ACh release. The Journal Of Physiology 2004, 561: 657-670. PMID: 15486020, PMCID: PMC1665378, DOI: 10.1113/jphysiol.2004.071712.Peer-Reviewed Original ResearchConceptsLocal ACh releaseACh releaseGABAergic neuronesCholinergic neuronesSeptohippocampal cholinergicMedial septum/diagonal bandHistamine-induced activationGABAergic cell typesReceptor-selective antagonistHippocampal theta rhythmIndirect mechanismsConcentration-dependent mannerAtropine methylbromideHippocampal arousalGABAergic functionHistaminergic systemTuberomammillary nucleusCholinergic systemReceptor subtypesDiagonal bandHistamine effectSelective antagonistAlzheimer's diseaseGABAergic nucleusNeurodegenerative disorders