2016
Recent Updates in the Management of Triple Negative Breast Cancer
Sanft T, Moran M. Recent Updates in the Management of Triple Negative Breast Cancer. TouchREVIEWS In Oncology & Haematology 2016, 12: 36. DOI: 10.17925/ohr.2016.12.01.36.Peer-Reviewed Original ResearchTriple-negative breast cancerNegative breast cancerBreast cancerLocoregional treatment optionsComplete pathologic responseNeoadjuvant chemotherapyPathologic responseResidual diseaseTreatment optionsAggressive subtypeNew agentsCancerDruggable targetsDisease biologyRecent updatesFurther researchChemotherapyPatientsTherapySubtypesDisease
2015
Radiation therapy in the locoregional treatment of triple-negative breast cancer
Moran MS. Radiation therapy in the locoregional treatment of triple-negative breast cancer. The Lancet Oncology 2015, 16: e113-e122. PMID: 25752562, DOI: 10.1016/s1470-2045(14)71104-0.Peer-Reviewed Original ResearchMeSH KeywordsBiomarkers, TumorDecision Support TechniquesDose Fractionation, RadiationFemaleGenetic Predisposition to DiseaseHumansMastectomyNeoplasm Recurrence, LocalPatient SelectionPhenotypePredictive Value of TestsRadiation ToleranceRadiotherapy, AdjuvantRisk AssessmentRisk FactorsTreatment OutcomeTriple Negative Breast NeoplasmsConceptsTriple-negative breast cancerBreast conservation therapyConservation therapyBreast cancerTreatment decisionsRadiation therapyWhole breast radiation therapy
2014
Should triple-negative breast cancer (TNBC) subtype affect local-regional therapy decision making?
Moran MS. Should triple-negative breast cancer (TNBC) subtype affect local-regional therapy decision making? American Society Of Clinical Oncology Educational Book 2014, e32-6. PMID: 24857120, DOI: 10.14694/edbook_am.2014.34.e32.Peer-Reviewed Original ResearchConceptsTriple-negative breast cancerLocal-regional relapseBreast cancer therapySporadic triple-negative breast cancerBreast cancerEarly-stage triple-negative breast cancerYounger ageAggressive biologic characteristicsBreast conservation approachHER2-positive subgroupContralateral breast cancerWhole breast irradiationDefinitive treatment strategyNegative breast cancer subtypeHypothesis-generating dataPartial breast irradiationBreast cancer subtypesBRCA1 mutation carriersSystemic chemotherapyAdvanced diseaseRandomized trialsGuideline recommendationsLuminal tumorsBreast irradiationTNBC subtypes