2011
A prospective, multicenter trial of complementary and alternative medicine (CAM) utilization by patients undergoing definitive breast radiotherapy.
Moran M, Yang J, Ma S, Gaudreau B, Higgins S, Weidhaas J, Wilson L, Peschel R, Fass D, Rockwell S. A prospective, multicenter trial of complementary and alternative medicine (CAM) utilization by patients undergoing definitive breast radiotherapy. Journal Of Clinical Oncology 2011, 29: 241-241. DOI: 10.1200/jco.2011.29.27_suppl.241.Peer-Reviewed Original ResearchCAM useRadiation therapyStage 0Relaxation/stress reductionTreatment-related symptomsLarge prospective studiesChance of cureAlternative medicine utilizationUtilization of CAMPaucity of dataYounger ptsStudy nursesMulticenter trialSymptom reliefProspective studyBreast radiotherapySkin assessmentHigh prevalenceMedicine utilizationAlternative medicineCAM practicesRT centersAssessment scoresHigher education levelSignificant differencesBreast cancers in U.S. residing Indian-Pakistani versus non-Hispanic White women: comparative analysis of clinical-pathologic features, treatment, and survival
Moran MS, Gonsalves L, Goss DM, Ma S. Breast cancers in U.S. residing Indian-Pakistani versus non-Hispanic White women: comparative analysis of clinical-pathologic features, treatment, and survival. Breast Cancer Research And Treatment 2011, 128: 543-551. PMID: 21301957, PMCID: PMC3235412, DOI: 10.1007/s10549-011-1362-0.Peer-Reviewed Original ResearchConceptsBreast conservation surgeryAge-adjusted incidenceBreast cancerAdjuvant radiationNHW womenInvasive diseaseHormone receptor-negative diseaseFemale breast cancer patientsNon-Hispanic white womenPost-mastectomy RTRates of breastClinical-pathologic featuresInvolved lymph nodesPercentage of patientsReceptor-negative diseasePost-mastectomy radiationBreast cancer mortalityBreast cancer patientsLarger tumor sizeYounger median ageRelative survival ratesSignificant differencesMultivariate regression analysisSEER databaseLymph nodes
2009
Local Therapy in BRCA1/2 Carriers with Operable Breast Cancer: Comparison of Breast Conservation and Mastectomy.
Pierce L, Phillips K, Griffith K, Buys S, Gaffney D, Moran M, Haffty B, Ben-David M, Garber J, Merajver S, Balmanya J, Meirovitz A, Domchek S. Local Therapy in BRCA1/2 Carriers with Operable Breast Cancer: Comparison of Breast Conservation and Mastectomy. Cancer Research 2009, 69: 959-959. DOI: 10.1158/0008-5472.sabcs-09-959.Peer-Reviewed Original ResearchContralateral breast cancerOperable breast cancerBreast conservationBreast cancerLocal therapyBRCA1/2 mutationsDistant failureClinical characteristicsBRCA1/2 carriersLocal failureBC-specific survivalDeleterious BRCA1/2 mutationsLocal treatment optionsInvasive lobular cancerGermline BRCA1/2 mutationsSignificant predictorsSignificant differencesOnly significant predictorAdjuvant chemotherapyBCT patientsOverall survivalContralateral breastLobular cancerLocal recurrenceRandomized trialsBreast cancer in young women (YBC): prevalence of BRCA1/2 mutations and risk of secondary malignancies across diverse racial groups
Haffty BG, Choi DH, Goyal S, Silber A, Ranieri K, Matloff E, Lee MH, Nissenblatt M, Toppmeyer D, Moran MS. Breast cancer in young women (YBC): prevalence of BRCA1/2 mutations and risk of secondary malignancies across diverse racial groups. Annals Of Oncology 2009, 20: 1653-1659. PMID: 19491284, DOI: 10.1093/annonc/mdp051.Peer-Reviewed Original ResearchConceptsBreast cancerSecondary malignanciesAge of onsetFamily historyBRCA1/2 mutationsYoung womenBRCA1/2 mutation statusBreast cancer diagnosisEligible womenSecond cancersInitial diagnosisBRCA1/2 statusMutation statusBRCA1/2 genesYounger ageKorean womenCancerMalignancyUncertain significanceCancer diagnosisCaucasiansWomenDiverse racial groupsFrequent mutationsSignificant differences
1998
Lobular carcinoma in situ as a component of breast cancer: The long-term outcome in patients treated with breast-conservation therapy
Moran M, Haffty B. Lobular carcinoma in situ as a component of breast cancer: The long-term outcome in patients treated with breast-conservation therapy. International Journal Of Radiation Oncology • Biology • Physics 1998, 40: 353-358. PMID: 9457821, DOI: 10.1016/s0360-3016(97)00573-7.Peer-Reviewed Original ResearchConceptsPercentage of patientsBreast cancer patientsLong-term outcomesConservative surgeryControl groupRadiation therapyHistologic componentsPrimary histologyLobular carcinomaCancer patientsBreast cancerComparable local control ratesDistant disease-free survivalTumor recurrence-free survivalDisease-free survivalLocal control rateRecurrence-free survivalAge of presentationBreast conservation therapyEstrogen receptor statusSignificant differencesReexcision specimenResidual LCISAdjuvant therapyBilateral disease
1997
Conservatively Treated Breast Cancer: Outcome by Histologic Subtype
Haffty B, Perrotta P, Ward B, Moran M, Beinfield M, McKhann C, Fischer D, Carter D. Conservatively Treated Breast Cancer: Outcome by Histologic Subtype. The Breast Journal 1997, 3: 7-14. DOI: 10.1111/j.1524-4741.1997.tb00134.x.Peer-Reviewed Original ResearchHistologic subtypeRecurrence-free rateRelapse rateDistant metastasisDuctal carcinomaRecurrence rateFocal invasionBreast cancerDistant recurrence-free survival rateIpsilateral breast tumor recurrence (IBTR) ratesIpsilateral breast tumor recurrenceRecurrence-free survival ratesDistant metastasis-free rateEarly-stage breast cancerSignificant differencesYale-New Haven HospitalPathological nodal involvementPrimary histologic subtypeBreast tumor recurrenceTumor recurrence rateBreast cancer patientsBreast conservation therapyMetastasis-free rateLow metastatic potentialAxillary dissection