Featured Publications
Potential Therapeutic Competition in Community-Living Older Adults in the U.S.: Use of Medications That May Adversely Affect a Coexisting Condition
Lorgunpai SJ, Grammas M, Lee DS, McAvay G, Charpentier P, Tinetti ME. Potential Therapeutic Competition in Community-Living Older Adults in the U.S.: Use of Medications That May Adversely Affect a Coexisting Condition. PLOS ONE 2014, 9: e89447. PMID: 24586786, PMCID: PMC3934884, DOI: 10.1371/journal.pone.0089447.Peer-Reviewed Original ResearchConceptsChronic conditionsMedication classesDisease guidelinesOlder adultsCommunity-living older adultsCross-sectional descriptive studyAdverse medication effectsCommon chronic conditionsMultiple chronic conditionsUse of medicationsClinical outcomesCoexisting conditionsMedication effectsClinical priorityMedicare claimsMedicationsStudy conditionsAdults 65Systematic reviewDescriptive studyPerson interviewsOlder AmericansAdultsFrequency of usePrevalence
2018
Evidence supporting the best clinical management of patients with multimorbidity and polypharmacy: a systematic guideline review and expert consensus
Muth C, Blom JW, Smith SM, Johnell K, Gonzalez‐Gonzalez A, Nguyen TS, Brueckle M, Cesari M, Tinetti M, Valderas JM. Evidence supporting the best clinical management of patients with multimorbidity and polypharmacy: a systematic guideline review and expert consensus. Journal Of Internal Medicine 2018, 285: 272-288. PMID: 30357955, DOI: 10.1111/joim.12842.Peer-Reviewed Original ResearchConceptsGuideline reviewReview of medicationsCoordination of careHeterogeneity of patientsBetter clinical managementSelf-management issuesRisk prediction modelAriadne principlesMedication appropriatenessInformational continuityTreatment optionsMedical historyPatient preferencesClinical managementPsychosocial assessmentTreatment benefitCare planningCare plansMultimorbidityFeasible interventionExpert consensusHealthcare providersPatientsClinical decisionPolypharmacy