Wanting-liking dissociation and altered dopaminergic functioning: Similarities between internet gaming disorder and tobacco use disorder
Ma X, Wang M, Zhou W, Zhang Z, Ni H, Jiang A, Zheng Y, Du X, Potenza M, Dong G. Wanting-liking dissociation and altered dopaminergic functioning: Similarities between internet gaming disorder and tobacco use disorder. Journal Of Behavioral Addictions 2024, 13: 596-609. PMID: 38635338, PMCID: PMC11220823, DOI: 10.1556/2006.2024.00011.Peer-Reviewed Original ResearchInternet gaming disorderTobacco use disorderIGD participantsGaming disorderCue-craving taskImplicit Association TestBrain-behavior mechanismsHealthy control participantsImplicit association test resultsFunctional MRI dataNeuromelanin-sensitive MRIIncentive sensitizationAddiction severityDopaminergic involvementDSM-5Dopaminergic functionDopaminergic systemPotential dissociationUse disorderControl participantsBrain featuresHedonic responsesAssociation TestGaming motivesNeural featuresrTMS effects on urges and severity of tobacco use disorder operate independently of a retrieval-extinction component and involve frontal-striatal pathways
Li S, Ma X, Chen H, Wang M, Zheng Y, Yang B, Ni H, Potenza M, Dong G. rTMS effects on urges and severity of tobacco use disorder operate independently of a retrieval-extinction component and involve frontal-striatal pathways. Journal Of Affective Disorders 2024, 349: 21-31. PMID: 38190858, DOI: 10.1016/j.jad.2024.01.048.Peer-Reviewed Original ResearchDorsolateral prefrontal cortexRepetitive transcranial magnetic stimulationSmoking cravingFunctional connectivityTobacco use disorderBrain regionsRetrieval-extinction procedureLeft dorsolateral prefrontal cortexSimilar neural correlatesFrontal-striatal pathwaysStandard repetitive transcranial magnetic stimulationUse disordersMedial frontal gyrusIncreased functional connectivitySham repetitive transcranial magnetic stimulationExecutive controlSmoking cuesNeural correlatesTranscranial magnetic stimulationBrain responsesFrontal gyrusGreater activationLess activationSmoking urgesBilateral insula