Anesthetic effects on regional CBF, BOLD, and the coupling between task‐induced changes in CBF and BOLD: An fMRI study in normal human subjects
Qiu M, Ramani R, Swetye M, Rajeevan N, Constable RT. Anesthetic effects on regional CBF, BOLD, and the coupling between task‐induced changes in CBF and BOLD: An fMRI study in normal human subjects. Magnetic Resonance In Medicine 2008, 60: 987-996. PMID: 18816821, PMCID: PMC2716171, DOI: 10.1002/mrm.21759.Peer-Reviewed Original ResearchConceptsCerebral blood flowLow-dose sevofluraneRegional cerebral blood flowTask-induced changesBaseline cerebral blood flowBlood oxygen level-dependent (BOLD) signalAbsence of anesthesiaHealthy human subjectsHuman subjectsNormal human subjectsLevel-dependent signalFunctional MR imagingVascular measuresAnesthetic agentsBlood flowAnesthetic effectSevofluraneFunctional MRI dataAnesthesia conditionsAnesthesiaMR imagingAuditory regionsOxidative metabolismAuditory stimuliFMRI study