2002
Antimicrobial Activities of BMS-284756 Compared with Those of Fluoroquinolones and β-Lactams against Gram-Positive Clinical Isolates
Bassetti M, Dembry L, Farrel P, Callan D, Andriole V. Antimicrobial Activities of BMS-284756 Compared with Those of Fluoroquinolones and β-Lactams against Gram-Positive Clinical Isolates. Antimicrobial Agents And Chemotherapy 2002, 46: 234-238. PMID: 11751142, PMCID: PMC126992, DOI: 10.1128/aac.46.1.234-238.2002.Peer-Reviewed Original ResearchConceptsBMS-284756Clinical isolatesGram-positive clinical isolatesResistant coagulase-negative staphylococciBeta-hemolytic streptococciAmoxicillin-clavulanic acidPositive clinical isolatesResistant Staphylococcus aureusCoagulase-negative staphylococciPiperacillin-tazobactamStreptococcus viridansStreptococcus pneumoniaeStaphylococcus aureusΒ-lactamsActive agentsIsolatesCeftriaxoneAntibacterial activityImipenemMoxifloxacinPneumoniaeViridansFluoroquinolones
2001
Comparative antimicrobial activity of gatifloxacin with ciprofloxacin and beta-lactams against gram-positive bacteria
Bassetti M, Dembry L, Farrel P, Callan D, Andriole V. Comparative antimicrobial activity of gatifloxacin with ciprofloxacin and beta-lactams against gram-positive bacteria. Diagnostic Microbiology And Infectious Disease 2001, 41: 143-148. PMID: 11750168, DOI: 10.1016/s0732-8893(01)00298-x.Peer-Reviewed Original ResearchConceptsAmoxicillin/clavulanic acidPiperacillin/tazobactamClavulanic acidMethicillin-susceptible S. aureusPenicillin-nonsusceptible Streptococcus pneumoniaeMethicillin-sensitive S. epidermidisMethicillin-resistant coagulase-negative staphylococciGram-positive infectionsViridans group streptococciCoagulase-negative staphylococciPromising new fluoroquinoloneActive agentsNew fluoroquinoloneStreptococcal isolatesGroup streptococciVitro antibacterial activityClinical isolatesStreptococcus pneumoniaeComparative antimicrobial activityStaphylococcal isolatesClinical useEnterococcal isolatesImipenemGatifloxacinE. faecalis
1998
Molecular Analysis of Glycopeptide-ResistantEnterococcus faecium Isolates Collected from Michigan Hospitals over a 6-Year Period
Thal L, Donabedian S, Robinson-Dunn B, Chow J, Dembry L, Clewell D, Alshab D, Zervos M. Molecular Analysis of Glycopeptide-ResistantEnterococcus faecium Isolates Collected from Michigan Hospitals over a 6-Year Period. Journal Of Clinical Microbiology 1998, 36: 3303-3308. PMID: 9774583, PMCID: PMC105319, DOI: 10.1128/jcm.36.11.3303-3308.1998.Peer-Reviewed Original ResearchMeSH KeywordsAnti-Bacterial AgentsBacterial Typing TechniquesChromosomes, BacterialCross InfectionDNA, BacterialDrug Resistance, MicrobialElectrophoresis, Gel, Pulsed-FieldEnterococcus faeciumGene Transfer TechniquesGenes, BacterialGram-Positive Bacterial InfectionsHumansMichiganMolecular EpidemiologyNucleic Acid HybridizationPlasmidsVancomycinConceptsExtended-care facilityPulsed-field gel electrophoresisEnterococcus faecium isolatesFaecium isolatesClonal disseminationVancomycin-resistant E. faeciumStrain typesE. faecium isolatesVancomycin-resistant E. faecium isolatesIntrahospital disseminationSpread of resistanceMichigan hospitalsMajority of isolatesPatientsHospitalClinical isolatesGentamicin resistanceVanA geneErythromycin resistanceE. faeciumVancomycin resistanceType M2VanB genesMolecular relatednessMost isolates
1995
Invasive Candida guilliermondii infection: in vitro susceptibility studies and molecular analysis.
Vazquez J, Lundstrom T, Dembry L, Chandrasekar P, Boikov D, Parri M, Zervos M. Invasive Candida guilliermondii infection: in vitro susceptibility studies and molecular analysis. Bone Marrow Transplantation 1995, 16: 849-53. PMID: 8750282.Peer-Reviewed Original ResearchConceptsHigh-dose amphotericin BMinimum inhibitory concentration (MIC) rangeSustained neutropeniaPurulent pericarditisAplastic anemiaC. guilliermondiiInhibitory concentration rangePoor responseClinical isolatesAmphotericin BProlonged durationHigh MICsInitial misidentificationTherapyEnvironmental isolatesIsolatesControl strainMolecular analysisNeutropeniaPericarditisFungemiaAnemiaBMTFlucytosineAmB