2008
Evaluating the process of care in nonvariceal upper gastrointestinal haemorrhage: a survey of expert vs. non‐expert gastroenterologists
ESRAILIAN E, GRALNEK IM, JENSEN D, LAINE L, DULAI GS, EISEN G, SPIEGEL BM. Evaluating the process of care in nonvariceal upper gastrointestinal haemorrhage: a survey of expert vs. non‐expert gastroenterologists. Alimentary Pharmacology & Therapeutics 2008, 28: 1199-1208. PMID: 18729846, DOI: 10.1111/j.1365-2036.2008.03838.x.Peer-Reviewed Original ResearchConceptsHigh-risk bleedingProcess of careIntravenous proton pump inhibitorsNonvariceal upper gastrointestinal hemorrhageUpper gastrointestinal tract hemorrhageLarge-channel endoscopeUpper gastrointestinal hemorrhageUse of hemoclipsGastrointestinal tract hemorrhageProton pump inhibitorsChoice of endoscopeNasogastric lavageGastrointestinal hemorrhageTract hemorrhagePromotility agentsContinuous infusionPump inhibitorsGuideline complianceWide variationBleedingHemorrhageGastroenterologistsVignette surveyCareEndoscope
1992
Indications, Technique, and Complications of Balloon Tamponade for Variceal Gastrointestinal Bleeding
Cook D, Laine L. Indications, Technique, and Complications of Balloon Tamponade for Variceal Gastrointestinal Bleeding. Journal Of Intensive Care Medicine 1992, 7: 212-218. PMID: 10147943, DOI: 10.1177/088506669200700408.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsBalloon tamponadeAcute upper gastrointestinal haemorrhageVariceal gastrointestinal bleedingUpper gastrointestinal hemorrhageBalloon insertionGastrointestinal bleedingGastrointestinal hemorrhageEsophageal varicesPotential complicationsTherapeutic endoscopyTimely treatmentTamponadeComplicationsVaricesBleedingSclerotherapyHemorrhagePatientsEndoscopyHemostatisEndoscopic therapy for acute nonvariceal upper gastrointestinal hemorrhage: A meta-analysis
Cook D, Guyatt G, Salena B, Laine L. Endoscopic therapy for acute nonvariceal upper gastrointestinal hemorrhage: A meta-analysis. Gastroenterology 1992, 102: 139-148. PMID: 1530782, DOI: 10.1016/0016-5085(92)91793-4.Peer-Reviewed Original ResearchConceptsAcute nonvariceal upper gastrointestinal hemorrhageNonvariceal upper gastrointestinal hemorrhageUpper gastrointestinal hemorrhageEndoscopic hemostatic therapyEndoscopic therapyGastrointestinal hemorrhageHemostatic therapyEndoscopic treatmentFlat pigmented spotUpper gastrointestinal bleedingDuplicate independent reviewForm of therapyEnglish-language literatureActive bleedingFurther bleedingGastrointestinal bleedingEndoscopic featuresInjection therapyAdherent clotRelevant trialsSurgery ratesVisible vesselLaser therapyBleedingTherapyProspective evaluation of immediate versus delayed refeeding and prognostic value of endoscopy in patients with upper gastrointestinal hemorrhage
Laine L, Cohen H, Brodhead J, Cantor D, Garcia F, Mosquera M. Prospective evaluation of immediate versus delayed refeeding and prognostic value of endoscopy in patients with upper gastrointestinal hemorrhage. Gastroenterology 1992, 102: 314-316. PMID: 1727765, DOI: 10.1016/0016-5085(92)91816-m.Peer-Reviewed Original ResearchConceptsMallory-Weiss tearUpper gastrointestinal hemorrhageGastrointestinal hemorrhagePrognostic valueRegular dietMajor upper gastrointestinal hemorrhageClean-based ulcersEndoscopic evidenceHospital courseRecurrent bleedingEndoscopic findingsMajor hemorrhageClinical evidenceProspective evaluationVs. 5Entry criteriaClean baseVs. 2Lower riskPatientsUlcersUrgent interventionVs. 1HemorrhageTears
1989
Multipolar electrocoagulation in the treatment of peptic ulcers with nonbleeding visible vessels. A prospective, controlled trial.
Laine L. Multipolar electrocoagulation in the treatment of peptic ulcers with nonbleeding visible vessels. A prospective, controlled trial. Annals Of Internal Medicine 1989, 110: 510-4. PMID: 2647014, DOI: 10.7326/0003-4819-110-7-510.Peer-Reviewed Original ResearchConceptsNonbleeding visible vesselMultipolar electrocoagulationVisible vesselControl groupMajor upper gastrointestinal hemorrhageMean transfusion requirementSham-controlled trialUpper gastrointestinal hemorrhageUnstable vital signsSafety of treatmentCost of hospitalizationUnits of bloodEndoscopic evidenceGastrointestinal hemorrhageTransfusion requirementsUrgent surgeryEmergency surgeryHospital daysEndoscopic treatmentOverall mortalityPeptic ulcerCounty HospitalAspirate samplesDiagnostic endoscopyTreatment groups
1987
Multipolar Electrocoagulation in the Treatment of Active Upper Gastrointestinal Tract Hemorrhage
Laine L. Multipolar Electrocoagulation in the Treatment of Active Upper Gastrointestinal Tract Hemorrhage. New England Journal Of Medicine 1987, 316: 1613-1617. PMID: 3295547, DOI: 10.1056/nejm198706253162601.Peer-Reviewed Original ResearchConceptsUpper gastrointestinal tract hemorrhageUpper gastrointestinal hemorrhageGastrointestinal tract hemorrhageMultipolar electrocoagulationGastrointestinal hemorrhageTract hemorrhageActive upper gastrointestinal hemorrhageNonvariceal upper gastrointestinal hemorrhageBloody nasogastric aspirateTerms of hemostasisMallory-Weiss tearUnstable vital signsUnits of bloodTransfusion requirementsActive bleedingHospital courseEmergency surgeryHospital daysNasogastric aspirateNonsurgical therapyVascular malformationsMean costHemorrhagePatientsVital signs