2014
Ultrasound-enhanced ocular delivery of dexamethasone sodium phosphate: an in vivo study
Nabili M, Shenoy A, Chawla S, Mahesh S, Liu J, Geist C, Zderic V. Ultrasound-enhanced ocular delivery of dexamethasone sodium phosphate: an in vivo study. Journal Of Therapeutic Ultrasound 2014, 2: 6. PMID: 24921047, PMCID: PMC4036608, DOI: 10.1186/2050-5736-2-6.Peer-Reviewed Original ResearchDexamethasone sodium phosphateAqueous humor samplesUnique anatomyDrug concentrationsSham-treated samplesVivo studiesOcular drug deliveryEye cupRabbit modelClinical settingAnatomical barriersOcular drugsHistological analysisOphthalmic drugsSodium phosphateResultsAn increaseCorneaEpithelial disorganizationEffective drug deliveryDrug deliveryOcular deliveryDrugsUltrasoundDeliveryMin
2013
Ultrasound-Enhanced Delivery of Antibiotics and Anti-Inflammatory Drugs Into the Eye
Nabili M, Patel H, Mahesh SP, Liu J, Geist C, Zderic V. Ultrasound-Enhanced Delivery of Antibiotics and Anti-Inflammatory Drugs Into the Eye. Ultrasound In Medicine & Biology 2013, 39: 638-646. PMID: 23415283, PMCID: PMC3770302, DOI: 10.1016/j.ultrasmedbio.2012.11.010.Peer-Reviewed Original ResearchConceptsOphthalmic drugsLong-term survival studiesSodium fluoresceinAnti-inflammatory drugsTreatment parameter combinationUltrasound-enhanced deliveryTopical administrationHistologic analysisSurvival studiesCorneaCorneal permeabilityDexamethasoneEpithelial layerTherapeutic drugsRabbit corneaStatistical significanceDrug dexamethasoneDrugsTobramycinUltrasoundEyesDeliveryFuture investigationsAdministrationDrug delivery