2021
A Circulating Exosome RNA Signature Is a Potential Diagnostic Marker for Pancreatic Cancer, a Systematic Study
Wu Y, Zeng H, Yu Q, Huang H, Fervers B, Chen ZS, Lu L. A Circulating Exosome RNA Signature Is a Potential Diagnostic Marker for Pancreatic Cancer, a Systematic Study. Cancers 2021, 13: 2565. PMID: 34073722, PMCID: PMC8197236, DOI: 10.3390/cancers13112565.Peer-Reviewed Original ResearchPancreatic cancerHealthy individualsRNA signatureChronic pancreatitisHealthy controlsExosome RNASimilar differential patternsPancreatic cancer detectionPotential diagnostic markerDisease stageTumor tissueCancerDiagnostic markerEarly detectionPancreatitisSignificant differencesCancer detectionDifferential patternsDifferential expressionExosomesExosome proteinsRNA-seq dataIndividualsRNAPatients
2010
Influence of GSTs, CYP2E1 and mEH polymorphisms on 1, 3-butadiene-induced micronucleus frequency in Chinese workers
Tan H, Wang Q, Wang A, Ye Y, Feng N, Feng X, Lu L, Au W, Zheng Y, Xia Z. Influence of GSTs, CYP2E1 and mEH polymorphisms on 1, 3-butadiene-induced micronucleus frequency in Chinese workers. Toxicology And Applied Pharmacology 2010, 247: 198-203. PMID: 20637790, DOI: 10.1016/j.taap.2010.07.006.Peer-Reviewed Original ResearchConceptsGenotypes of GSTM1Higher MN frequencyMicronucleus frequencyChromosomal damageNon-exposed healthy individualsMN frequencyPolymorphisms of GSTM1Lower micronucleus frequencyBD exposure levelsPeripheral lymphocytesHealthy individualsMEH polymorphismsMetabolic polymorphismsBD exposureGSTM1CYP2E1Exposure levelsHigh groupCBMN assayLow exposureHuman carcinogenPCR-RFLPChromosome damageIntermediate groupPresent study