2020
Zinc supplement ameliorates phthalates-induced reproductive toxicity in male rats
Gao HT, Di QN, Qian LL, Lu L, Li RX, Cao WX, Xu Q. Zinc supplement ameliorates phthalates-induced reproductive toxicity in male rats. Chemosphere 2020, 246: 125828. PMID: 31927381, DOI: 10.1016/j.chemosphere.2020.125828.Peer-Reviewed Original ResearchConceptsZinc supplementsMale ratsReproductive toxicityReproductive functionProtein expressionSteroidogenic proteinsSub-chronic exposureMale reproductive functionMale reproductive toxicityPathological examinationRat testicular cellsRatsTesticular cellsLHHealth risksExposureSerumSupplementsUrineToxicityMixture exposureTestisAlterationsExpressionToxicity evaluation
2018
High tRNA Transferase NSUN2 Gene Expression is Associated with Poor Prognosis in Head and Neck Squamous Carcinoma
Lu L, Zhu G, Zeng H, Xu Q, Holzmann K. High tRNA Transferase NSUN2 Gene Expression is Associated with Poor Prognosis in Head and Neck Squamous Carcinoma. Cancer Investigation 2018, 36: 246-253. PMID: 29775108, DOI: 10.1080/07357907.2018.1466896.Peer-Reviewed Original ResearchConceptsPotential independent prognostic markerShorter overall survivalIndependent prognostic markerHigher mortality riskNeck squamous carcinomaPotential therapeutic targetRandom-effects modelOverall survivalSquamous carcinomaPoor prognosisPrognostic valuePrognostic markerMortality riskTherapeutic targetHNSCCNormal tissuesCell developmentExpressionGene expressionRNA methylationPatientsCarcinomaPrognosisNSUN2Important role